Compounds of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime which are
useful as cholinergic agents
    1.
    发明授权
    Compounds of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime which are useful as cholinergic agents 失效
    可作为纯化剂使用的1,2,5,6-四氢吡啶-3-羰氧基二甲氧基化合物的化合物

    公开(公告)号:US5219872A

    公开(公告)日:1993-06-15

    申请号:US19256

    申请日:1987-02-26

    CPC分类号: C07D211/70

    摘要: Compounds useful in the treatment of Alzheimer's disease, senile dementia, or memory disorders which have the formula ##STR1## in which R represents a hydrogen atom, a linear, branched or cyclic alkyl radical, saturated or unsaturated, containing up to 8 carbon atoms, possibly substituted by a free or esterified carboxy radical or R represents an aralkyl radical containing up to 10 carbon atoms and R' represents a linear or branched, saturated or unsaturated, alkyl radical, containing up to 8 carbon atoms, a radical --COalk.sub.1 or a radical --(CH.sub.2).sub.2 N(alk.sub.2).sub.2, alk.sub.1 and alk.sub.2 representing an alkyl radical containing up to 8 carbon atoms, as well as their addition salts with acids. Also compositions containing the same, method of preparation and method of treatment using the same.

    摘要翻译: 用于治疗阿尔茨海默病,老年性痴呆或记忆障碍的化合物,其具有式(IMAGE),其中R表示氢原子,含有至多8个碳原子的饱和或不饱和的直链,支链或环状烷基, 可能被游离或酯化的羧基取代,或R表示含有至多10个碳原子的芳烷基,R'表示含有至多8个碳原子的直链或支链,饱和或不饱和的烷基,基团-COalk1或 自由基 - (CH2)2N(alk2)2,alk1和alk2代表含有至多8个碳原子的烷基,以及它们与酸的加成盐。 还含有相同的组合物,制备方法和使用其的处理方法。

    Process for preparing 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oximes
    2.
    发明授权
    Process for preparing 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oximes 失效
    制备1,2,5,6-四氢吡啶-3-甲醛肟的方法

    公开(公告)号:US5532375A

    公开(公告)日:1996-07-02

    申请号:US313616

    申请日:1994-09-30

    CPC分类号: C07D211/70

    摘要: Compounds useful in the treatment of Alzheimer's disease, senile dementia, or memory disorders which have the formula ##STR1## in which R represents a hydrogen atom, a linear, branched or cyclic alkyl radical, saturated or unsaturated, containing up to 8 carbon atoms, possibly substituted by a free or esterified carboxy radical or R represents an aralkyl radical containing up to 10 carbon atoms and R' represents a linear or branched, saturated or unsaturated, alkyl radical, containing up to 8 carbon atoms, a radical --COalk.sub.1 or a radical --(CH.sub.2).sub.2 N(alk.sub.2).sub.2, alk.sub.1 and alk.sub.2 representing an alkyl radical containing up to 8 carbon atoms, as well as their addition salts with acids. Also compositions containing the same, method of preparation and method of treatment using the same.

    摘要翻译: 用于治疗阿尔茨海默病,老年性痴呆或记忆障碍的化合物,其具有式(IMAGE),其中R表示氢原子,含有至多8个碳原子的饱和或不饱和的直链,支链或环状烷基, 可能被游离或酯化的羧基取代,或R表示含有至多10个碳原子的芳烷基,R'表示含有至多8个碳原子的直链或支链,饱和或不饱和的烷基,基团-COalk1或 自由基 - (CH2)2N(alk2)2,alk1和alk2代表含有至多8个碳原子的烷基,以及它们与酸的加成盐。 还含有相同的组合物,制备方法和使用其的处理方法。

    Process for preparing 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime
compounds
    3.
    发明授权
    Process for preparing 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime compounds 失效
    制备1,2,5,6-四氢吡啶-3-甲醛肟化合物的方法

    公开(公告)号:US5391754A

    公开(公告)日:1995-02-21

    申请号:US39826

    申请日:1993-03-30

    CPC分类号: C07D211/70

    摘要: Compounds useful in the treatment of Alzheimer's disease, senile dementia, or memory disorders which have the formula ##STR1## in which R represents a hydrogen atom, a linear, branched or cyclic alkyl radical, saturated or unsaturated, containing up to 8 carbon atoms, possibly substituted by a free or esterified carboxy radical or R represents an aralkyl radical containing up to 10 carbon atoms and R' represents a linear or branched, saturated or unsaturated, alkyl radical, containing up to 8 carbon atoms, a radical --COalk.sub.1 or a radical --(CH.sub.2).sub.2 N(alk.sub.2).sub.2, alk.sub.1 and alk.sub.2 representing an alkyl radical containing up to 8 carbon atoms, as well as their addition salts with acids. Also compositions containing the same, method of preparation and method of treatment using the same.

    摘要翻译: 用于治疗阿尔茨海默病,老年性痴呆或记忆障碍的化合物,其具有式(IMAGE),其中R表示氢原子,含有至多8个碳原子的饱和或不饱和的直链,支链或环状烷基, 可能被游离或酯化的羧基取代,或R表示含有至多10个碳原子的芳烷基,R'表示含有至多8个碳原子的直链或支链,饱和或不饱和的烷基,基团-COalk1或 自由基 - (CH2)2N(alk2)2,alk1和alk2代表含有至多8个碳原子的烷基,以及它们与酸的加成盐。 还含有相同的组合物,制备方法和使用其的处理方法。