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1.发明申请POLYMER MATRIX COMPOSITIONS COMPRISING A HIGH CONCENTRATION OF BIO-FERMENTED SODIUM HYALURONATE AND USES THEREOF 有权包含生物发酵的高碘酸钠的高浓度聚合物基质组合物及其用途公开(公告)号：US20170020912A1
公开(公告)日：2017-01-26
申请号：US14818810
申请日：2015-08-05
发明人： Kevin Drizen , Jai Velusamy
IPC分类号： A61K31/728 , A61K47/14 , A61K47/38 , A61K9/00 , A61K31/196 , A61K31/455 , A61K31/047 , A61K47/36 , A61K47/10 , A61K31/197
CPC分类号： A61K31/728 , A61K9/0014 , A61K9/0034 , A61K9/06 , A61K31/047 , A61K31/196 , A61K31/197 , A61K31/455 , A61K45/06 , A61K47/10 , A61K47/14 , A61K47/36 , A61K47/38 , A61K2300/00 , A61L26/0023 , A61L26/0052 , A61L26/0066 , A61L26/008 , Y02A50/473 , Y02A50/481 , C08L5/08 , C08L1/02 , C08L71/02
摘要： The present invention relates to stable polymer matrix compositions comprising high concentrations (from about 1.5% w/w to about 3.5% w/w) sodium hyaluronate obtained from a Streptococcus zooepidemicus source and a non-ionic polymer. The polymer matrix composition further comprises polyethylene glycol and methylparaben, and utilizes ingredients that are of pharmaceutical or compendial grade. The polymer matrix compositions may optionally comprise an active ingredient. The present polymer matrix compositions may be used in the treatment of wounds, burns, certain dermatological conditions, vaginal dryness, and in topical, transdermal delivery and sustained release of active ingredients.
摘要翻译： 本发明涉及包含从动物疫苗链球菌源和非离子聚合物获得的高浓度（约1.5％w / w至约3.5％w / w）透明质酸钠的稳定聚合物基质组合物。 聚合物基质组合物还包含聚乙二醇和对羟基苯甲酸甲酯，并且使用药物级或级别级的成分。 聚合物基质组合物可任选地包含活性成分。 本发明的聚合物基质组合物可用于治疗伤口，烧伤，某些皮肤病学条件，阴道干燥以及局部，透皮递送和活性成分的持续释放。
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公开(公告)号：US09821005B2
公开(公告)日：2017-11-21
申请号：US14818810
申请日：2015-08-05
发明人： Kevin Drizen , Jai Velusamy
IPC分类号： A61K31/728 , A61L26/00 , A61K47/38 , A61K47/10 , A61K9/00 , A61K31/047 , A61K31/196 , A61K47/14 , A61K45/06 , A61K31/197 , A61K31/455 , A61K9/06 , A61K47/36
CPC分类号： A61K31/728 , A61K9/0014 , A61K9/0034 , A61K9/06 , A61K31/047 , A61K31/196 , A61K31/197 , A61K31/455 , A61K45/06 , A61K47/10 , A61K47/14 , A61K47/36 , A61K47/38 , A61K2300/00 , A61L26/0023 , A61L26/0052 , A61L26/0066 , A61L26/008 , Y02A50/473 , Y02A50/481 , C08L5/08 , C08L1/02 , C08L71/02
摘要： The present invention relates to stable polymer matrix compositions comprising high concentrations (from about 1.5% w/w to about 3.5% w/w) sodium hyaluronate obtained from a Streptococcus zooepidemicus source and a non-ionic polymer. The polymer matrix composition further comprises polyethylene glycol and methylparaben, and utilizes ingredients that are of pharmaceutical or compendial grade. The polymer matrix compositions may optionally comprise an active ingredient. The present polymer matrix compositions may be used in the treatment of wounds, burns, certain dermatological conditions, vaginal dryness, and in topical, transdermal delivery and sustained release of active ingredients.
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公开(公告)号：US10322142B2
公开(公告)日：2019-06-18
申请号：US15727820
申请日：2017-10-09
发明人： Kevin Drizen , Jai Velusamy
IPC分类号： A61K9/00 , A61K9/06 , C08L1/02 , C08L5/08 , A61K47/10 , A61K47/36 , A61K47/38 , A61L26/00 , C08L71/02 , A61K31/047 , A61K31/196 , A61K31/197 , A61K31/455 , A61K31/728 , A61K45/06 , A61K47/14
摘要： The present invention relates to stable polymer matrix compositions comprising high concentrations (from about 1.5% w/w to about 3.5% w/w) sodium hyaluronate obtained from a Streptococcus zooepidemicus source and a non-ionic polymer. The polymer matrix composition further comprises polyethylene glycol and methylparaben, and utilizes ingredients that are of pharmaceutical or compendial grade. The polymer matrix compositions may optionally comprise an active ingredient. The present polymer matrix compositions may be used in the treatment of wounds, burns, certain dermatological conditions, vaginal dryness, and in topical, transdermal delivery and sustained release of active ingredients.
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4.发明申请公开(公告)号：US20180042957A1
公开(公告)日：2018-02-15
申请号：US15727820
申请日：2017-10-09
发明人： Kevin Drizen , Jai Velusamy
IPC分类号： A61K31/728 , C08L71/02 , A61K31/196 , A61K47/10 , A61K9/06 , A61K47/36 , A61K47/38 , A61L26/00 , A61K31/455 , A61K31/197 , A61K45/06 , A61K47/14 , C08L5/08 , C08L1/02 , A61K31/047 , A61K9/00
CPC分类号： A61K31/728 , A61K9/0014 , A61K9/0034 , A61K9/06 , A61K31/047 , A61K31/196 , A61K31/197 , A61K31/455 , A61K45/06 , A61K47/10 , A61K47/14 , A61K47/36 , A61K47/38 , A61K2300/00 , A61L26/0023 , A61L26/0052 , A61L26/0066 , A61L26/008 , Y02A50/473 , Y02A50/481 , C08L5/08 , C08L1/02 , C08L71/02
摘要： The present invention relates to stable polymer matrix compositions comprising high concentrations (from about 1.5% w/w to about 3.5% w/w) sodium hyaluronate obtained from a Streptococcus zooepidemicus source and a non-ionic polymer. The polymer matrix composition further comprises polyethylene glycol and methylparaben, and utilizes ingredients that are of pharmaceutical or compendial grade. The polymer matrix compositions may optionally comprise an active ingredient. The present polymer matrix compositions may be used in the treatment of wounds, burns, certain dermatological conditions, vaginal dryness, and in topical, transdermal delivery and sustained release of active ingredients.
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