公开(公告)号：US20100023101A1

公开(公告)日：2010-01-28

申请号：US12278233

申请日：2005-02-02

申请人： Gordon George Wallace ,  Simon Edward Moulton ,  Philip Gregory Whitten ,  Carol Mary Lynam

发明人： Gordon George Wallace ,  Simon Edward Moulton ,  Philip Gregory Whitten ,  Carol Mary Lynam

IPC分类号： A61N1/05 ,  A61K38/00 ,  A61K31/7088 ,  A61F2/00 ,  A61B5/0408

CPC分类号： A61N1/0452 ,  A61B5/0408 ,  A61L27/443 ,  A61L27/54 ,  A61L2300/222 ,  A61L2300/232 ,  A61L2300/256 ,  A61L2300/258 ,  A61L2300/406 ,  A61L2300/414 ,  A61L2300/43 ,  A61L2400/12 ,  A61N1/0464 ,  A61N1/0496 ,  A61N1/05 ,  B82Y30/00 ,  C08K5/0008 ,  C08L5/08 ,  C08L5/10

摘要： The present invention relates to biocompatible composites, in particular biocompatible nanotube composites in the form of a fiber mat and/or film structure, comprising nanotubes and at least one biomolecule. The invention also relates to a process for preparing a biocompatible composite involving (i) forming a dispersing media comprising nanotubes and at least one biomolecule; and either (ii) introducing the dispersing media of step (i) into a coagulating media optionally comprising at least one biomolecule so as to form a continuous fiber; or (iii) filtering the dispersing media of step (i). Alternatively, the process involves (i) forming a dispersing media comprising nanotubes; and (ii) introducing the dispersing media of step (i) into a coagulating media comprising at least one biomolecule so as to form a continuous fiber. The biocompatible composite is useful as a medical device, preferably in a bio-electrode, bio-fuel cell or substrates for electronically stimulated bio-growth.

摘要翻译： 本发明涉及生物相容性复合材料，特别是包含纳米管和至少一种生物分子的纤维垫和/或膜结构形式的生物相容性纳米管复合材料。 本发明还涉及制备生物相容性复合物的方法，其包括（i）形成包含纳米管和至少一种生物分子的分散介质; 和（ii）将步骤（i）的分散介质引入任选包含至少一种生物分子的凝结介质中以形成连续纤维; 或（iii）过滤步骤（i）的分散介质。 或者，该方法包括（i）形成包含纳米管的分散介质; 和（ii）将步骤（i）的分散介质引入包含至少一种生物分子的凝结介质中以形成连续纤维。 生物相容性复合物可用作医疗装置，优选用于生物电极，生物燃料电池或用于电子刺激的生物生长的底物。