公开(公告)号：US4188486A

公开(公告)日：1980-02-12

申请号：US856969

申请日：1977-12-02

申请人： Goro Tsukamoto ,  Koichiro Yoshino ,  Toshihiko Kohno ,  Masahiro Taguchi ,  Katsumi Dezawa ,  Hajime Kagaya ,  Keiso Ito ,  Takashi Nose

发明人： Goro Tsukamoto ,  Koichiro Yoshino ,  Toshihiko Kohno ,  Masahiro Taguchi ,  Katsumi Dezawa ,  Hajime Kagaya ,  Keiso Ito ,  Takashi Nose

IPC分类号： C07D235/18 ,  C07D401/02

CPC分类号： C07D235/18

摘要： 2-Substituted benzimidazole compounds of the formula: ##STR1## wherein R.sub.1 is hydrogen, halogen, lower alkyl or lower alkoxy, and R.sub.2 is hydrogen or lower alkyl with the proviso that R.sub.1 and R.sub.2 do not stand for hydrogen simultaneously and, when R.sub.1 is hydrogen, R.sub.2 cannot mean a methyl group at the 6th position on the pyridin-2-yl group or methyl an isobutyl group on the phenyl group; are useful as anti-inflammatory agents and/or analgesics.

摘要翻译： 2-取代的下式的苯并咪唑化合物：其中R 1是氢，卤素，低级烷基或低级烷氧基，R 2是氢或低级烷基，条件是R 1和R 2 不同时代表氢，当R1为氢时，R2不能指吡啶-2-基上第六位的甲基或苯基上的甲基异丁基; 可用作抗炎剂和/或止痛剂。