公开(公告)号：US20140296140A1

公开(公告)日：2014-10-02

申请号：US14306938

申请日：2014-06-17

申请人： Greg S. JOHNSON ,  Bala SUBRAMANIAM ,  Fenghui Niu

发明人： Greg S. JOHNSON ,  Bala SUBRAMANIAM ,  Fenghui Niu

IPC分类号： B01J8/00

CPC分类号： B01J8/006 ,  A61J3/02 ,  B01D9/0013 ,  B01D9/0054 ,  B01D11/0411 ,  B01D46/0068 ,  B01J3/008 ,  B01J4/002 ,  Y02P20/544

摘要： An equipment assembly for preparing, harvesting and collecting particles is disclosed. The assembly comprises a tandem filter system with one or more high pressure filters, one or more low pressure filters and one or more collection vessel. Particles can be prepared, harvested and collected continuously, semi-continuously or in a batch-type operation. A tandem filter system and its method of use are also disclosed. Particles made with the assembly and according the instant methods are also disclosed. The assembly provides improved particle harvesting and collection over other systems and permits continuous particle formation, in particular by dispersion of a solute-containing process fluid within a supercritical anti-solvent.

摘要翻译： 公开了一种用于制备，收集和收集颗粒的设备组件。 组件包括具有一个或多个高压过滤器，一个或多个低压过滤器和一个或多个收集容器的串联过滤器系统。 可以连续，半连续或间歇式操作来制备，收获和收集颗粒。 还公开了一种串联过滤系统及其使用方法。 还公开了使用组装制成的颗粒和根据即时方法制备的颗粒。 该组件在其它系统上提供改进的颗粒收获和收集，并允许连续的颗粒形成，特别是通过在超临界反溶剂中分散含溶质的工艺流体。