公开(公告)号：US5766224A

公开(公告)日：1998-06-16

申请号：US627688

申请日：1996-04-02

申请人： Clifton A. Alferness ,  John M. Adams ,  Gregory M. Ayers ,  Hugo X. Gonzalez

发明人： Clifton A. Alferness ,  John M. Adams ,  Gregory M. Ayers ,  Hugo X. Gonzalez

IPC分类号： A61N1/05 ,  A61N1/39

CPC分类号： A61N1/3962 ,  A61N1/0587

摘要： A post-surgical atrial cardioverting, atrial pacing, and ventricular pacing system and lead system provides for cardioverting the atria, pacing the atria, and/or pacing the ventricles of the heart of a post-surgical heart patient. The system includes a first lead and a second lead providing a pair of atrial cardioverting electrodes, an atrial pacing electrode, and a ventricular pacing electrode. The electrodes are electrically isolated from each other. The system further includes at least one anchor releasably disposing the electrodes beneath the skin of the patient with each atrial cardioverting electrode electrically contacting a respective given one of the atria, the atrial pacing electrode electrically contacting one of the atria, and the ventricular pacing electrode electrically contacting a ventricle. The system further includes at least one of an external cardiovertor coupled to the cardioverting electrodes for cardioversion, an external atrial pacer coupled to the atrial pacing electrode and one of the atrial cardioverting electrodes for pacing the atria, and an external ventricular pacer coupled to the ventricular pacing electrode and one of the atrial cardioverting electrodes for pacing the ventricles.

摘要翻译： 手术后心房心律转复，心房起搏和心室起搏系统和牵引系统提供心脏转移心房，起搏心房和/或起搏手术后心脏病人心脏的心室。 该系统包括提供一对心房心脏转复电极，心房起搏电极和心室起搏电极的第一引线和第二引线。 电极彼此电隔离。 所述系统还包括至少一个锚定器，其可释放地将电极设置在患者皮肤下方，每个心房心脏转复电极与相应的心房起搏器电气接触，心房起搏电极与心房起搏器电气接触， 接触心室。 该系统还包括耦合到用于心脏复律的复律电极的外部心脏转换器中的至少一个，耦合到心房起搏电极的外部心房起搏器和用于起搏心房的心房心律转换电极之一和与心室联接的外部心室起搏器 起搏电极和心房心律转复电极之一用于起搏心室。

公开(公告)号：US5350402A

公开(公告)日：1994-09-27

申请号：US67688

申请日：1993-05-26

申请人： Kenneth R. Infinger ,  Gregory M. Ayers ,  Darrell O. Wagner ,  John M. Adams

发明人： Kenneth R. Infinger ,  Gregory M. Ayers ,  Darrell O. Wagner ,  John M. Adams

IPC分类号： A61N1/365 ,  A61N1/362 ,  A61N1/39

CPC分类号： A61N1/3956 ,  A61N1/3622 ,  A61N1/395 ,  A61N1/3987

摘要： An implantable atrial defibrillator and method provides cardioverting electrical energy to the atria of a human heart in need of cardioversion. The atrial defibrillator includes a first detector for detecting R waves of the heart, a second detector for detecting T waves of the heart, and a third detector for detecting atrial activity of the heart. An atrial fibrillation detector is responsive to the third detector for determining when the atria of the heart are in need of cardioversion. A cardioverting stage applies the cardioverting electrical energy to the atria of the heart when the atria of the heart are in need of cardioversion, after the second detector detects a T wave, and in timed relation to an R wave detected by the first detector after the detected T wave is completed. The atrial defibrillator includes a timer for timing a predetermined delay time after the T wave is detected, which delay time must be completed before the atria are cardioverted in timed relation to a detected R wave to assure that the detected T wave is completed.

摘要翻译： 可植入心房除颤器和方法为需要心脏复律的心脏心房提供心律转复的电能。 心房除颤器包括用于检测心脏的R波的第一检测器，用于检测心脏的T波的第二检测器，以及用于检测心脏的心房活动的第三检测器。 心房颤动检测器响应于第三检测器，用于确定心脏心房何时需要心脏复律。 当心脏的心房需要心脏复律时，在第二检测器检测到T波之后，以及在与第一检测器之后检测到的R波的定时关系中，心脏转换的电能将心脏转换的能量应用于心脏的心房 检测到T波完成。 心房除颤器包括：定时器，用于在检测到T波之后定时预定的延迟时间，该延迟时间必须在心跳与检测的R波的定时关系转换之前完成，以确保检测到的T波完成。

公开(公告)号：US5814081A

公开(公告)日：1998-09-29

申请号：US835169

申请日：1997-04-07

申请人： Gregory M. Ayers ,  John M. Adams

发明人： Gregory M. Ayers ,  John M. Adams

IPC分类号： A61N1/39

CPC分类号： A61N1/3956 ,  A61N1/395

摘要： An implantable atrial defibrillator includes a lead system having a plurality of electrodes to deliver a cardioverting pulse to atria of a heart, for sensing A waves of the heart, and for sensing R waves of the heart. A first detector detects the A waves sensed by the lead system and a second detector detects the R waves sensed by the lead system. An inhibit stage defines an inhibit time period responsive to each detected R wave and an output provides the cardioverting pulse to the lead system responsive to an A wave being detected. The inhibit stage precludes provision of the cardioverting pulse during each inhibit time period.

摘要翻译： 可植入心房除颤器包括引导系统，该引导系统具有多个电极，用于将心律转换脉冲输送到心脏的心房，用于感测心脏的波浪，并用于感测心脏的R波。 第一检测器检测由引导系统感测的A波，第二检测器检测由引导系统感测的R波。 禁止级定义响应于每个检测到的R波的禁止时间周期，并且输出响应于检测到的A波而将引导系统提供心跳转换脉冲。 禁止阶段排除了在每个禁止时间段期间提供的复律脉冲。

公开(公告)号：US12102161B2

公开(公告)日：2024-10-01

申请号：US18417908

申请日：2024-01-19

申请人： George Papadopoulos ,  John M. Adams

发明人： George Papadopoulos ,  John M. Adams

IPC分类号： A42B3/16 ,  A42B3/32 ,  H04R1/02 ,  H04R1/10

CPC分类号： A42B3/166 ,  A42B3/324 ,  H04R1/028 ,  H04R1/1008 ,  H04R1/1083

摘要： A helmet features a sound management mechanism within a hard exterior shell and an interior of expanded polystyrene foam. Ear cups embedded within the shell surround the ears, with a torus-shaped soft material forming a seal against the wearer's head. The helmet allows the transition of ear cups between engaged and disengaged positions. The engaged position is against the head. The disengaged position is away from the head, allowing easy placement and removing of the helmet. Positions may be transitioned using one hand. The helmet may include lateral adjustment of ear cups, and some versions incorporate electronic audio features like noise cancellation, communication capabilities, and wireless connectivity.

公开(公告)号：US08574247B2

公开(公告)日：2013-11-05

申请号：US13291875

申请日：2011-11-08

申请人： John M. Adams ,  Thomas G. Goff

发明人： John M. Adams ,  Thomas G. Goff

IPC分类号： A61B17/22

CPC分类号： A61B17/22012 ,  A61B17/22022 ,  A61B2017/22024 ,  A61B2017/22025 ,  A61B2017/22062 ,  A61B2017/22098

摘要： A valvuloplasty system includes a balloon adapted to be placed adjacent leaflets of a valve. The balloon is inflatable with a liquid. The system further includes a shock wave generator within the balloon that produces shock waves that propagate through the liquid for impinging upon the valve. The shock wave generator is moveable within the balloon to vary shock wave impingement on the valve.

摘要翻译： 瓣膜成形术系统包括适于邻近瓣膜的小叶放置的球囊。 气球用液体充气。 该系统还包括气囊内的冲击波发生器，其产生传播通过液体冲击阀的冲击波。 冲击波发生器可以在气球内移动，以改变阀上的冲击波冲击。

公开(公告)号：US08568429B2

公开(公告)日：2013-10-29

申请号：US13547026

申请日：2012-07-11

申请人： Stefan J. M. Kraemer ,  John M. Adams ,  Stephen T. Vincent

发明人： Stefan J. M. Kraemer ,  John M. Adams ,  Stephen T. Vincent

IPC分类号： A61B19/00

CPC分类号： A61B17/068 ,  A61B17/00234 ,  A61B17/0644 ,  A61B17/07207 ,  A61B2017/003 ,  A61B2017/00827 ,  A61B2017/00867 ,  A61B2017/07214 ,  A61B2017/2905 ,  A61B2017/2926 ,  A61B2017/306

摘要： The invention provides a device, assembly, and method for transoral endoscopic restoration of a gastroesophageal flap valve. The invention also provides a self-steering and self-closing tissue fixation device for tissue fixation, and an invaginator device for gripping and maneuvering tissue. The restoration device includes a longitudinal member arranged for transoral placement into a stomach, a tissue shaper carried on the longitudinal member that causes stomach tissue to assume a shape related to a gastroesophageal flap, and a tissue fixation device that maintains the shaped stomach tissue in a shape approximating a gastroesophageal flap. The tissue shaper may include a mold. The device may include the invaginator device for gripping and maneuvering esophageal tissue to aid restoration of the gastroesophageal flap, and may include the tissue fixation device.

公开(公告)号：US08449504B2

公开(公告)日：2013-05-28

申请号：US12616582

申请日：2009-11-11

申请人： Brett Carter ,  John McKenzie ,  John M. Adams ,  Brett Cross ,  Travis Marsot

发明人： Brett Carter ,  John McKenzie ,  John M. Adams ,  Brett Cross ,  Travis Marsot

IPC分类号： A61M5/162

CPC分类号： A61M5/158 ,  A61M5/14244 ,  A61M5/14248 ,  A61M5/162 ,  A61M5/1626 ,  A61M5/16831 ,  A61M39/26 ,  A61M2005/14252 ,  A61M2005/1585 ,  A61M2005/1588

摘要： Disclosed is a drug infusion system comprising a drug infusion device having a reservoir, a window for viewing the contents of the reservoir, a cannula arranged to be deployed beneath the skin of a patient, and an actuator configured to be manually actuated to drive a medicament from the reservoir to the cannula. The system also has a cannula cover and a needle handle that holds a needle for insertion into the patient. The cannula cover and needle handle are detachably attached to the drug infusion device, and each is attachable to the other. The device further comprises a septum and a septum pincher to seal the device. The device also comprises a pumping mechanism, part of which are a last-dose lock-out mechanism and an occlusion detection mechanism, both of which operate on the same actuator.

摘要翻译： 公开了一种药物输注系统，其包括具有储存器的药物输注装置，用于观察储存器的内容物的窗口，布置成展开在患者皮肤下方的套管以及构造成手动致动以驱动药物的致动器 从储存器到套管。 该系统还具有套管盖和针柄，其保持用于插入患者体内的针头。 套管盖和针柄可拆卸地附接到药物输注装置，并且每个可附接到另一个。 该装置还包括隔膜和隔膜夹子以密封该装置。 该装置还包括泵送机构，其中一部分是最后剂量锁定机构和遮挡检测机构，两者都在相同的致动器上操作。

公开(公告)号：US20130116714A1

公开(公告)日：2013-05-09

申请号：US13291875

申请日：2011-11-08

申请人： John M. Adams ,  Thomas G. Goff

发明人： John M. Adams ,  Thomas G. Goff

IPC分类号： A61B17/22

CPC分类号： A61B17/22012 ,  A61B17/22022 ,  A61B2017/22024 ,  A61B2017/22025 ,  A61B2017/22062 ,  A61B2017/22098

摘要： A valvuloplasty system comprises a balloon adapted to be placed adjacent leaflets of a valve. The balloon is inflatable with a liquid. The system further includes a shock wave generator within the balloon that produces shock waves that propagate through the liquid for impinging upon the valve. The shock wave generator is moveable within the balloon to vary shock wave impingement on the valve.

摘要翻译： 瓣膜成形术系统包括适于邻近瓣膜的小叶放置的球囊。 气球用液体充气。 该系统还包括气囊内的冲击波发生器，其产生传播通过液体冲击阀的冲击波。 冲击波发生器可以在气球内移动，以改变阀上的冲击波冲击。

公开(公告)号：US20120330328A1

公开(公告)日：2012-12-27

申请号：US13604276

申请日：2012-09-05

申请人： Steve G. BAKER ,  Brett J. Carter ,  Stefan J.M. Kraemer ,  Clifton A. Alferness ,  John M. Adams

发明人： Steve G. BAKER ,  Brett J. Carter ,  Stefan J.M. Kraemer ,  Clifton A. Alferness ,  John M. Adams

IPC分类号： A61B17/03

CPC分类号： A61B17/0401 ,  A61B17/0469 ,  A61B17/064 ,  A61B17/068 ,  A61B2017/00827 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0419

摘要： Tissue fasteners carried on a tissue piercing deployment wire fasten tissue layers of a mammalian body together. The fasteners include a first member, a second member, and a connecting member extending between the first and second members. The first and second members are substantially parallel to each other. The fasteners may be deployed in limited spaces and in various applications including the restoration of a gastroesophageal flap valve.

摘要翻译： 携带在组织穿刺部署线上的组织紧固件将哺乳动物身体的组织层紧固在一起。 紧固件包括第一构件，第二构件和在第一构件和第二构件之间延伸的连接构件。 第一和第二构件基本上彼此平行。 紧固件可以在有限的空间和各种应用中部署，包括恢复胃食管瓣阀。

公开(公告)号：US07976500B2

公开(公告)日：2011-07-12

申请号：US12147283

申请日：2008-06-26

申请人： John M. Adams ,  Brett J. Carter

发明人： John M. Adams ,  Brett J. Carter

IPC分类号： A61M1/00

CPC分类号： A61M5/14248 ,  A61M5/14244 ,  A61M5/1452 ,  A61M5/16881 ,  A61M39/22 ,  A61M39/223 ,  A61M2005/14252 ,  A61M2005/1426 ,  A61M2039/224

摘要： A wearable infusion device comprises a reservoir that holds a liquid medicament, an outlet port that delivers the liquid medicament to a patient, a pump that holds a volume of the liquid medicament received from the reservoir and displaces substantially all of the volume of the liquid medicament when actuated, and at least a first valve, a second valve, and a third valve. The valves establish fluid connection between the reservoir and the pump when in a first valve configuration and establish fluid connection between the pump and the outlet when in a second valve configuration. At least two of the valves isolate the outlet from the reservoir when the valves are in the first valve configuration.

摘要翻译： 一种可佩戴的输注装置包括容纳液体药物的储存器，将液体药物输送给患者的出口端口，其保持从储存器接收的液体药物的体积，并基本上移动液体药物的大部分体积 当被致动时，以及至少第一阀，第二阀和第三阀。 当处于第一阀构造时，阀在储存器和泵之间建立流体连接，并且当处于第二阀配置时，在泵和出口之间建立流体连接。 当阀处于第一阀配置中时，至少有两个阀将出口与储存器隔离。