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公开(公告)号:US20230039456A1
公开(公告)日:2023-02-09
申请号:US17786129
申请日:2020-12-17
申请人: Gregory Matlashewski , Wen-Wei Zhang , Patrick Lypaczewski , The U.S.A., as represented by the Secretary, Department of Health and Human Services , Ohio State Innovation Foundation
发明人: Hira L. Nakhasi , Ranadhir Dey , Sreenivas Gannavaram , Subir Karmakar , Gregory Matlashewski , Abhay Satoskar , Wen-Wei Zhang , Patrick Lypaczewski
IPC分类号: A61K39/008 , C12N15/63 , C12N1/10 , A61P33/02
摘要: Disclosed herein are modified Leishmania species and compositions thereof, such as live, attenuated organisms, immunogenic compositions, vaccines, and pharmaceutical compositions. Further disclosed are methods related to the modified Leishmania species, such as methods of production and methods of use.