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公开(公告)号:US20230039456A1
公开(公告)日:2023-02-09
申请号:US17786129
申请日:2020-12-17
申请人: Gregory Matlashewski , Wen-Wei Zhang , Patrick Lypaczewski , The U.S.A., as represented by the Secretary, Department of Health and Human Services , Ohio State Innovation Foundation
发明人: Hira L. Nakhasi , Ranadhir Dey , Sreenivas Gannavaram , Subir Karmakar , Gregory Matlashewski , Abhay Satoskar , Wen-Wei Zhang , Patrick Lypaczewski
IPC分类号: A61K39/008 , C12N15/63 , C12N1/10 , A61P33/02
摘要: Disclosed herein are modified Leishmania species and compositions thereof, such as live, attenuated organisms, immunogenic compositions, vaccines, and pharmaceutical compositions. Further disclosed are methods related to the modified Leishmania species, such as methods of production and methods of use.
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公开(公告)号:US20160120844A1
公开(公告)日:2016-05-05
申请号:US14924605
申请日:2015-10-27
发明人: Kristy Ainslie , Eric Bachelder , Shalini Gautam , Kevin Peine , Abhay Satoskar
IPC分类号: A61K31/415 , A61K31/7048 , A61K45/06
CPC分类号: A61K31/415 , A61K31/7048 , A61K45/06 , Y02A50/409 , A61K2300/00
摘要: Compositions and methods for inhibiting Leishmaniasis using AIs are provided. Aspects provide compositions and methods for administering AIs alone or in combination with other compounds to infected hosts.
摘要翻译: 提供了使用AIs抑制利什曼病的组合物和方法。 方面提供用于单独或与其它化合物组合给受感染宿主的AI的组合物和方法。
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公开(公告)号:US20180185334A1
公开(公告)日:2018-07-05
申请号:US15867056
申请日:2018-01-10
发明人: Kristy Ainslie , Eric Bachelder , Shalini Gautam , Kevin Peine , Abhay Satoskar
IPC分类号: A61K31/415 , A61K31/7048 , A61K45/06
CPC分类号: A61K31/415 , A61K31/7048 , A61K45/06 , Y02A50/409 , A61K2300/00
摘要: Compositions and methods for inhibiting Leishmaniasis using AIs are provided. Aspects provide compositions and methods for administering AIs alone or in combination with other compounds to infected hosts.
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公开(公告)号:US09901569B2
公开(公告)日:2018-02-27
申请号:US14924605
申请日:2015-10-27
发明人: Kristy Ainslie , Eric Bachelder , Shalini Gautam , Kevin Peine , Abhay Satoskar
IPC分类号: A61K31/415 , A61K31/7048 , A61K45/06
CPC分类号: A61K31/415 , A61K31/7048 , A61K45/06 , Y02A50/409 , A61K2300/00
摘要: Compositions and methods for inhibiting Leishmaniasis using AIs are provided. Aspects provide compositions and methods for administering AIs alone or in combination with other compounds to infected hosts.
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