专利检索 ap:("Gregory Moore" OR "Rajat Varma" OR "Yoon Kyung Kim" OR "Rumana Rashid" OR "Eric W. Chang" OR "Alex Nisthal" OR "Juan Diaz" OR "Matthew Bernett" OR "Michael Hedvat") AND inv:"Alex Nisthal" 第 1 页

1.

发明申请
UNTARGETED AND TARGETED IL-10 FC-FUSION PROTEINS 有权

公开(公告)号：US20210171596A1

公开(公告)日：2021-06-10

申请号：US16798247

申请日：2020-02-21

申请人： Gregory Moore , Rajat Varma , Yoon Kyung Kim , Rumana Rashid , Eric W. Chang , Alex Nisthal , Juan Diaz , Matthew Bernett , Michael Hedvat

发明人： Gregory Moore , Rajat Varma , Yoon Kyung Kim , Rumana Rashid , Eric W. Chang , Alex Nisthal , Juan Diaz , Matthew Bernett , Michael Hedvat

IPC分类号： C07K14/54

摘要： The present invention provides untargeted and targeted IL-10-Fc fusion proteins, compositions and methods of use thereof. The targeted IL-10-Fc fusion proteins includes those that bind PD-1, TIGIT, CD8 and NKG2D.

2.

发明申请
TARGETED HETERODIMERIC FC FUSION PROTEINS CONTAINING IL-15/IL-15RA AND NKG2D ANTIGEN BINDING DOMAINS 审中-公开

公开(公告)号：US20200247862A1

公开(公告)日：2020-08-06

申请号：US16724118

申请日：2019-12-20

申请人： Matthew J. Bernett , John R. Desjarlais , Rajat Varma , Gregory Moore , Juan Diaz , Alex Nisthal , Ke Liu , Rumana Rashid , Eric Chang

发明人： Matthew J. Bernett , John R. Desjarlais , Rajat Varma , Gregory Moore , Juan Diaz , Alex Nisthal , Ke Liu , Rumana Rashid , Eric Chang

IPC分类号： C07K14/54 , C07K16/28 , A61P35/00

摘要： The present invention is directed to a novel targeted heterodimeric Fc fusion proteins comprising an IL-15/IL-15Rα Fc fusion protein and an NKG2D antigen binding domain Fc fusion proteins.