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1.发明授权Data storage cartridge loading and unloading mechanism, drive door mechanism and data drive 失效数据存储盒装卸机构，驱动门机构和数据驱动公开(公告)号：US07739701B1
公开(公告)日：2010-06-15
申请号：US11283864
申请日：2005-11-22
IPC分类号： G11B17/03
CPC分类号： G11B17/0405 , G11B17/0407 , G11B17/0434 , G11B17/0436
摘要： The present invention provides loading and unloading mechanisms for data storage cartridges, drive door mechanisms for data drives, and data drives comprising such loading and unloading and/or drive door mechanisms. Embodiments of the cartridge loading and unloading mechanisms, drive door mechanisms and/or data drives, of the present invention can operate in a manner such that the drive door of the data drive is fully closed before the disk medium is exposed, e.g., before opening of the associated shutter of the cartridge. An embodiment of the cartridge loading and unloading mechanism of the present invention can be powered by the same drive motor assembly that is used to move or transport the cartridge to the optical head assembly used for writing and/or reading of data from the disk medium of the cartridge. Embodiments of the cartridge loading and unloading mechanisms and drive door mechanisms of the present invention can fit within a standard configuration for a data drive. Embodiments of the cartridge loading and unloading mechanisms, drive door mechanisms and/or data drives of the present invention can provide for reliable operation, ease of assembly, as well as simplification of the parts and components necessary for the reliable operation of the loading and unloading mechanism, drive door mechanism and/or data drive.
摘要翻译： 本发明提供了用于数据存储盒，数据驱动器的驱动门机构和包括这种装载和卸载和/或驱动门机构的数据驱动装置的装载和卸载机构。 本发明的盒装载和卸载机构，驱动门机构和/或数据驱动器的实施例可以以这样的方式操作，使得数据驱动器的驱动门在盘介质暴露之前完全关闭，例如在打开之前 的盒的相关快门。 本发明的盒装载和卸载机构的一个实施例可以由相同的驱动马达组件来驱动，驱动马达组件用于将盒移动或运送到用于从盘介质写入和/或读取数据的光学头组件 墨盒。 本发明的盒装载和卸载机构和驱动门机构的实施例可以适合数据驱动器的标准配置。 本发明的盒装载和卸载机构，驱动门机构和/或数据驱动器的实施例可以提供可靠的操作，易于组装以及简化对于装载和卸载的可靠操作所需的部件 机构，驱动门机构和/或数据驱动器。
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2.发明授权公开(公告)号：US08079040B2
公开(公告)日：2011-12-13
申请号：US11447033
申请日：2006-06-06
CPC分类号： G11B17/032 , G11B17/041
摘要： The present invention provides loading and unloading mechanisms, and data drives for data storage cartridges. Embodiments of the cartridge loading and unloading mechanisms for a data storage cartridge may: operate in a manner such that the drive door of the data drive may be fully closed before the disk medium is exposed, e.g., before opening of the associated shutter of the cartridge; be powered by the same drive motor assembly that is used to move or transport the cartridge to the optical head assembly used for writing and/or reading of data from the disk medium of the cartridge; and may fit within a standard configuration for a data drive. Embodiments of the cartridge loading and unloading mechanisms, as well as the data drives, may provide reliable operation, ease of assembly, and of the parts and components necessary for the reliable operation, and positive data cartridge positioning, as well as minimizing backlash in the drive motor/gear assembly.
摘要翻译： 本发明提供了用于数据存储盒的装载和卸载机构以及数据驱动器。 用于数据存储盒的盒装载和卸载机构的实施例可以以这样的方式操作，使得数据驱动器的驱动门可以在盘介质暴露之前完全关闭，例如在打开相关联的盒的快门之前 ; 由用于将盒移动或运送到用于从盒的盘介质写入和/或读取数据的光学头组件的相同的驱动马达组件驱动; 并且可能适合数据驱动器的标准配置。 盒装载和卸载机构以及数据驱动器的实施例可以提供可靠的操作，易于组装以及可靠操作所需的部件和组件以及正数据盒定位，以及最小化 驱动电机/齿轮总成。
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3.发明授权System and method for reducing the placebo effect in controlled clinical trials 有权在对照临床试验中降低安慰剂效应的系统和方法公开(公告)号：US07983936B1
公开(公告)日：2011-07-19
申请号：US12909075
申请日：2010-10-21
申请人： Maurizio Fava , David Schoenfeld
发明人： Maurizio Fava , David Schoenfeld
摘要： A method and system for performing a clinical trial having a reduced placebo effect is disclosed. The method includes randomizing study participants into three or more treatment groups and performing a first phase of testing on the groups. In a typical embodiment, the first phase of testing includes administering an active treatment to a first group, and administering a placebo to a second group and to a third group. Responders and non-responders are determined for each group. A second phase of testing is then performed. The second phase of testing includes administering the placebo to non-responders in the first group, administering the active treatment to non-responders in the second group, and administering the placebo to non-responders in the third group. The data from the first phase of testing and from the second phase of testing is pooled and analyzed to determine response rates to active treatment and placebo.
摘要翻译： 公开了一种用于进行安慰剂效果降低的临床试验的方法和系统。 该方法包括将研究参与者随机分为三个或更多个治疗组，并对组进行第一阶段的测试。 在典型的实施方案中，第一阶段的测试包括向第一组施用主动治疗，以及向第二组和第三组施用安慰剂。 确定每个组的响应者和不应答者。 然后执行第二阶段的测试。 测试的第二阶段包括对第一组中的无应答者施用安慰剂，对第二组中的不应答者进行积极治疗，并将第三组中的无应答者施用于安慰剂。 汇集和分析来自第一阶段测试和第二阶段测试的数据，以确定对主动治疗和安慰剂的反应率。
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公开(公告)号：US08145505B1
公开(公告)日：2012-03-27
申请号：US13176091
申请日：2011-07-05
申请人： Maurizio Fava , David Schoenfeld
发明人： Maurizio Fava , David Schoenfeld
摘要： A method and system for performing a clinical trial having a reduced placebo effect is disclosed. The method includes randomizing study participants into three or more treatment groups and performing a first phase of testing on the groups. In a typical embodiment, the first phase of testing includes administering an active treatment to a first group, and administering a placebo to a second group and to a third group. Responders and non-responders are determined for each group. A second phase of testing is then performed. The second phase of testing includes administering the placebo to non-responders in the first group, administering the active treatment to non-responders in the second group, and administering the placebo to non-responders in the third group. The data from the first phase of testing and from the second phase of testing is pooled and analyzed to determine response rates to active treatment and placebo.
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5.发明授权System and method for reducing the placebo effect in controlled clinical trials 有权在对照临床试验中降低安慰剂效应的系统和方法公开(公告)号：US08145504B1
公开(公告)日：2012-03-27
申请号：US13156481
申请日：2011-06-09
申请人： Maurizio Fava , David Schoenfeld
发明人： Maurizio Fava , David Schoenfeld
摘要： A method and system for performing a clinical trial having a reduced placebo effect is disclosed. The method includes randomizing study participants into three or more treatment groups and performing a first phase of testing on the groups. In a typical embodiment, the first phase of testing includes administering an active treatment to a first group, and administering a placebo to a second group and to a third group. Responders and non-responders are determined for each group. A second phase of testing is then performed. The second phase of testing includes administering the placebo to non-responders in the first group, administering the active treatment to non-responders in the second group, and administering the placebo to non-responders in the third group. The data from the first phase of testing and from the second phase of testing is pooled and analyzed to determine response rates to active treatment and placebo.
摘要翻译： 公开了一种用于进行安慰剂效果降低的临床试验的方法和系统。 该方法包括将研究参与者随机分为三个或更多个治疗组，并对组进行第一阶段的测试。 在典型的实施方案中，第一阶段的测试包括向第一组施用主动治疗，以及向第二组和第三组施用安慰剂。 确定每个组的响应者和不应答者。 然后执行第二阶段的测试。 测试的第二阶段包括对第一组中的无应答者施用安慰剂，对第二组中的不应答者进行积极治疗，并将第三组中的无应答者施用于安慰剂。 汇集和分析来自第一阶段测试和第二阶段测试的数据，以确定对主动治疗和安慰剂的反应率。
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公开(公告)号：US07647235B1
公开(公告)日：2010-01-12
申请号：US10814852
申请日：2004-03-31
申请人： Maurizio Fava , David Schoenfeld
发明人： Maurizio Fava , David Schoenfeld
摘要： A method and system for performing a clinical trial having a reduced placebo effect is disclosed. The method includes randomizing study participants into three or more treatment groups and performing a first phase of testing on the groups. In a typical embodiment, the first phase of testing includes administering an active treatment to a first group, and administering a placebo to a second group and to a third group. Responders and non-responders are determined for each group. A second phase of testing is then performed. The second phase of testing includes administering the placebo to non-responders in the first group, administering the active treatment to non-responders in the second group, and administering the placebo to non-responders in the third group. The data from the first phase of testing and from the second phase of testing is pooled and analyzed to determine response rates to active treatment and placebo.
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公开(公告)号：US08219419B1
公开(公告)日：2012-07-10
申请号：US13403060
申请日：2012-02-23
申请人： Maurizio Fava , David Schoenfeld
发明人： Maurizio Fava , David Schoenfeld
摘要： A method and system for performing a clinical trial having a reduced placebo effect is disclosed. The method includes randomizing study participants into three or more treatment groups and performing a first phase of testing on the groups. In a typical embodiment, the first phase of testing includes administering an active treatment to a first group, and administering a placebo to a second group and to a third group. Responders and non-responders are determined for each group. A second phase of testing is then performed. The second phase of testing includes administering the placebo to non-responders in the first group, administering the active treatment to non-responders in the second group, and administering the placebo to non-responders in the third group. The data from the first phase of testing and from the second phase of testing is pooled and analyzed to determine response rates to active treatment and placebo.
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8.发明授权System and method for reducing the placebo effect in controlled clinical trials 有权在对照临床试验中降低安慰剂效应的系统和方法公开(公告)号：US07840419B1
公开(公告)日：2010-11-23
申请号：US12545562
申请日：2009-08-21
申请人： Maurizio Fava , David Schoenfeld
发明人： Maurizio Fava , David Schoenfeld
摘要： A method and system for performing a clinical trial having a reduced placebo effect is disclosed. The method includes randomizing study participants into three or more treatment groups and performing a first phase of testing on the groups. In a typical embodiment, the first phase of testing includes administering an active treatment to a first group, and administering a placebo to a second group and to a third group. Responders and non-responders are determined for each group. A second phase of testing is then performed. The second phase of testing includes administering the placebo to non-responders in the first group, administering the active treatment to non-responders in the second group, and administering the placebo to non-responders in the third group. The data from the first phase of testing and from the second phase of testing is pooled and analyzed to determine response rates to active treatment and placebo.
摘要翻译： 公开了一种用于进行安慰剂效果降低的临床试验的方法和系统。 该方法包括将研究参与者随机分为三个或更多个治疗组，并对组进行第一阶段的测试。 在典型的实施方案中，第一阶段的测试包括向第一组施用主动治疗，以及向第二组和第三组施用安慰剂。 确定每个组的响应者和不应答者。 然后执行第二阶段的测试。 测试的第二阶段包括对第一组中的无应答者施用安慰剂，对第二组中的不应答者进行积极治疗，并将第三组中的无应答者施用于安慰剂。 汇集和分析来自第一阶段测试和第二阶段测试的数据，以确定对主动治疗和安慰剂的反应率。
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