公开(公告)号：US20220274965A1

公开(公告)日：2022-09-01

申请号：US17631257

申请日：2020-07-30

Applicant: GRIFFITH UNIVERSITY

Inventor： Mark Von Itzstein ,  Ibrahim El-Deeb ,  Larissa Heilig ,  Patrice Guillon

IPC: C07D405/04 ,  C07D405/14 ,  C07D471/04 ,  C07D491/056 ,  C07D495/04

Abstract: The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt thereof: Formula (I) In which R3 is selected from the group consisting of optionally substituted N-linked naphthotriazole, optionally substituted N-linked indazole, and certain N-linked triazoles. The present invention also relates to uses of the compounds in treating a disease, disorder or condition caused by viral infection, and pharmaceutical compositions comprising the compounds.

公开(公告)号：US20170290809A1

公开(公告)日：2017-10-12

申请号：US15508055

申请日：2015-09-07

Applicant: Griffith University

Inventor： Mark Von Itzstein ,  Ibrahim El-Deeb ,  Larissa Dirr ,  Patrice Guillon ,  Moritz Winger

IPC: A61K31/4192 ,  A61K31/41 ,  A61K31/4025 ,  A61K31/403 ,  A61K31/351 ,  A61K31/36

CPC classification number: A61K31/4192 ,  A61K31/351 ,  A61K31/36 ,  A61K31/4025 ,  A61K31/403 ,  A61K31/41 ,  A61K2300/00 ,  C07D405/04

Abstract: The present invention relates to compounds which are found to exhibit an antiviral effect. The compounds are modulators of the activity of the viral haemagglutinin and/or neuraminidase enzymes.

公开(公告)号：US10028938B2

公开(公告)日：2018-07-24

申请号：US15508055

申请日：2015-09-07

Applicant: Griffith University

Inventor： Mark Von Itzstein ,  Ibrahim El-Deeb ,  Larissa Dirr ,  Patrice Guillon ,  Moritz Winger

IPC: A61K31/4192 ,  A61K31/351 ,  A61K31/36 ,  A61K31/4025 ,  A61K31/403 ,  A61K31/41

CPC classification number: A61K31/4192 ,  A61K31/351 ,  A61K31/36 ,  A61K31/4025 ,  A61K31/403 ,  A61K31/41 ,  A61K2300/00 ,  C07D405/04

Abstract: The present invention relates to compounds which are found to exhibit an antiviral effect. The compounds are modulators of the activity of the viral haemagglutinin and/or neuraminidase enzymes.