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公开(公告)号:US20140135474A1
公开(公告)日:2014-05-15
申请号:US13899698
申请日:2013-05-22
申请人: Guido Cappuccilli , Robert Crea , Randy Shen , Craig A. Hokanson , Peter B. Kirk , David R. Liston
发明人: Guido Cappuccilli , Robert Crea , Randy Shen , Craig A. Hokanson , Peter B. Kirk , David R. Liston
IPC分类号: C07K14/78
CPC分类号: C07K14/78 , C07K16/18 , C07K16/22 , C07K16/241 , C07K2317/21 , C07K2317/52 , C07K2318/20 , C12N15/1044 , C40B40/10
摘要: Fibronectin Type III (FN3) polypeptide libraries are described, along with their use in identifying fibronectin-type binding peptides having high binding affinities, e.g., greater than 300 nM, for VEGFR2 or Axl proteins.
摘要翻译: 描述了纤连蛋白III型(FN3)多肽文库以及它们在鉴定对VEGFR2或Ax1蛋白具有高结合亲和力(例如大于300nM)的纤连蛋白型结合肽的用途。