公开(公告)号：US20160083359A1

公开(公告)日：2016-03-24

申请号：US14948775

申请日：2015-11-23

Applicant: H. Lundbeck A/S

Inventor： Benny Bang-Andersen ,  André Faldt ,  Arne Mørk ,  Heidi Lopez De Diego ,  René Holm ,  Tine Bryan Stensbøl ,  Lone Munch Ringgard ,  Michael J. Mealy ,  Michael Harold Rock ,  Jørgen Brodersen ,  Morten Jørgensen ,  Nicholas Moore

IPC: C07D295/096

CPC classification number: A61K31/495 ,  A61K9/14 ,  A61P25/22 ,  C07D295/096 ,  Y10T428/2982

Abstract: 1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on SERT, 5-HT3 and 5-HT1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.

Abstract translation: 1- [2-（2,4-二甲基苯基硫烷基）苯基]哌嗪显示出对SERT，5-HT3和5-HT1A的有效活性，并且可以用于治疗认知障碍，特别是抑郁症患者。