Solid dose form of nanoparticulate naproxen
    8.
    发明授权
    Solid dose form of nanoparticulate naproxen 失效
    固体剂型纳米颗粒萘普生

    公开(公告)号:US6165506A

    公开(公告)日:2000-12-26

    申请号:US148332

    申请日:1998-09-04

    摘要: Described are solid dose nanoparticulate naproxen formulations having high rates of dissolution. The solid dose nanoparticulate naproxen formulations can comprise an alkali compound, which functions to increase the dissolution rate of the naproxen following administration. Alternatively, the solid dose nanoparticulate naproxen formulation can comprise an alkali compound and an acidic compound, which can react together to form carbon dioxide. The formed carbon dioxide can also aid in increasing the dissolution rate of the naproxen following administration. Also described are solid dose nanoparticulate naproxen formulations having a decreased concentration of a binder/disintegrant agent. Such compositions also provide an increased rate of dissolution of naproxen following administration.

    摘要翻译: 描述了具有高溶解速率的固体剂量纳米颗粒萘普生制剂。 固体剂量纳米颗粒萘普生制剂可以包含碱性化合物,其用于在施用后增加萘普生的溶出速率。 或者,固体剂量纳米颗粒萘普生制剂可以包含可以一起反应形成二氧化碳的碱性化合物和酸性化合物。 形成的二氧化碳还可以有助于在施用后增加萘普生的溶解速率。 还描述了具有降低的粘合剂/崩解剂的浓度的固体剂量纳米颗粒萘普生制剂。 这样的组合物还提供萘普生在给药后的溶出速率增加。

    Network communications bandwidth control
    10.
    发明申请
    Network communications bandwidth control 有权
    网络通信带宽控制

    公开(公告)号:US20050232151A1

    公开(公告)日:2005-10-20

    申请号:US10993268

    申请日:2004-11-19

    摘要: A method for controlling real time data communications over a packet based network comprises steps of dynamically measuring data packet loss between a receiver and a sender on the network, dynamically measuring data latency between the sender and receiver, and comparing the dynamically measured data packet loss to a loss limit and comparing the dynamically measured data latency to a latency limit. If one or both of the loss limit or the latency limit is exceeded, then the method may include reducing the rate of data transmission from the sender.

    摘要翻译: 一种用于控制基于分组的网络上的实时数据通信的方法包括以下步骤:动态测量网络上的接收机和发送者之间的数据分组丢失,动态测量发送方和接收方之间的数据等待时间,并将动态测量的数据分组丢失与 损失限制,并将动态测量的数据延迟与延迟限制进行比较。 如果超过损失限制或延迟限制中的一个或两个,则该方法可以包括降低从发送者的数据传输速率。