-
1.
公开(公告)号:US20190056324A1
公开(公告)日:2019-02-21
申请号:US15763935
申请日:2016-09-08
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Akinori ODA , Hiroshi SATOZONO , Tomomi SHINKE , Yohei TAKATA
Abstract: The present invention relates to a method for detecting an amyloid β oligomer which includes a test sample and thioflavin T are brought into contact with each other, fluorescence of the thioflavin T is measured to obtain time-resolved fluorescence spectra, the time-resolved fluorescence spectrum of time period t1 to t2 and the time-resolved fluorescence spectrum of time period t3 to t4 are respectively normalized to obtain normalized spectra (t1
-
公开(公告)号:US20220404280A1
公开(公告)日:2022-12-22
申请号:US17839568
申请日:2022-06-14
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Akinori ODA , Hiroshi SATOZONO
IPC: G01N21/64
Abstract: Provided is a method of quantifying a target substance present in a solvent comprises acquiring a first fluorescence decay curve and a second fluorescence decay curve to acquire some factors from the curves.
-
公开(公告)号:US20180273498A1
公开(公告)日:2018-09-27
申请号:US15763926
申请日:2016-08-15
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Akinori ODA , Hiroshi SATOZONO , Tomomi SHINKE , Yohei TAKATA
IPC: C07D277/66 , G01N33/52
CPC classification number: C07D277/66 , G01N33/52 , G01N33/6893 , G01N2333/4709
Abstract: The present invention relates to a method for purifying pure thioflavin T in having a step of preparing a thioflavin T solution in which crude thioflavin T is dissolved in a polar solvent, a step of bringing the thioflavin T solution into contact with a non-polar polymeric porous body, and a step of separating the thioflavin T solution after the contact from the non-polar polymeric porous body.
-
公开(公告)号:US20220357276A1
公开(公告)日:2022-11-10
申请号:US17858183
申请日:2022-07-06
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Akinori ODA , Hiroshi Satozono , Tomomi Shinke , Yohei Takata
Abstract: The present invention relates to a method for detecting an amyloid β oligomer which includes a test sample and thioflavin T are brought into contact with each other, fluorescence of the thioflavin T is measured to obtain time-resolved fluorescence spectra, the time-resolved fluorescence spectrum of time period t1 to t2 and the time-resolved fluorescence spectrum of time period t3 to t4 are respectively normalized to obtain normalized spectra (t1
-
-
-