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公开(公告)号：US11254724B2
公开(公告)日：2022-02-22
申请号：US16684110
申请日：2019-11-14
发明人： Sung Youb Jung , Young Jin Park , Jong Suk Lee , Jae Hyuk Choi , Chang Ki Lim , Se Chang Kwon
IPC分类号： C07K14/605 , A61K38/26 , A61K45/06 , A61K38/00
摘要： The present invention relates to a novel peptide of a glucagon derivative and a composition for preventing or treating obesity comprising the peptide as an active ingredient. The glucagon derivative according to the present invention shows a more excellent activating effect with regard to both glucagon-like peptide-1 receptors and glucagon receptors compared to native glucagon, and thus can be widely used as an effective agent for treating obesity.
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公开(公告)号：US11332508B2
公开(公告)日：2022-05-17
申请号：US16370057
申请日：2019-03-29
发明人： Euh Lim Oh , Jong Suk Lee , Young Jin Park , Chang Ki Lim , Sung Youb Jung , Se Chang Kwon
IPC分类号： A61K38/00 , C07K14/605 , A61K38/26 , A61P3/04 , A61P3/10 , A61K39/395 , C07K14/47 , C07K16/28 , A61K47/60 , A61P9/10 , A61P9/12
摘要： A a triple agonist having activities to all of glucagon, GLP-1, and GIP receptors is disclosed. Uses of the triple agonist are disclosed.
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公开(公告)号：US10400020B2
公开(公告)日：2019-09-03
申请号：US16024014
申请日：2018-06-29
发明人： Euh Lim Oh , Jong Suk Lee , Young Jin Park , Chang Ki Lim , Sung Youb Jung , Se Chang Kwon
IPC分类号： A61K38/00 , C07K14/605 , A61K38/26 , A61K39/395 , A61P3/04 , A61P3/10 , C07K16/28 , C07K14/47 , A61P9/12 , A61K47/60 , A61P9/10
摘要： The present invention relates to a long-acting conjugate of a triple agonist having activities to all of glucagon, GLP-1, and GIP receptors and uses thereof.
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公开(公告)号：US12018060B2
公开(公告)日：2024-06-25
申请号：US17499222
申请日：2021-10-12
发明人： Sung Youb Jung , Young Jin Park , Jong Suk Lee , Jae Hyuk Choi , Chang Ki Lim , Se Chang Kwon
IPC分类号： A61K38/26 , A61K45/06 , C07K14/605 , A61K38/00
CPC分类号： C07K14/605 , A61K38/26 , A61K45/06 , A61K38/00
摘要： The present invention relates to a novel peptide of a glucagon derivative and a composition for preventing or treating obesity comprising the peptide as an active ingredient. The glucagon derivative according to the present invention shows a more excellent activating effect with regard to both glucagon-like peptide-1 receptors and glucagon receptors compared to native glucagon, and thus can be widely used as an effective agent for treating obesity.
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公开(公告)号：US10981967B2
公开(公告)日：2021-04-20
申请号：US16263469
申请日：2019-01-31
发明人： Euh Lim Oh , Jong Suk Lee , Young Jin Park , Chang Ki Lim , Sung Youb Jung , Se Chang Kwon
IPC分类号： A61K38/00 , C07K14/605 , A61K38/26 , A61P3/04 , A61P3/10 , A61K39/395 , C07K14/47 , C07K16/28 , A61K47/60 , A61P9/10 , A61P9/12
摘要： A long-acting conjugate of a triple agonist which has activities to all of glucagon, GLP-1, and GIP receptors and uses thereof.
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公开(公告)号：US20190218269A1
公开(公告)日：2019-07-18
申请号：US16370057
申请日：2019-03-29
发明人： Euh Lim OH , Jong Suk Lee , Young Jin Park , Chang Ki Lim , Sung Youb Jung , Se Chang Kwon
IPC分类号： C07K14/605 , C07K16/28 , A61P3/10 , A61P3/04 , C07K14/47 , A61K38/26 , A61K39/395
CPC分类号： C07K14/605 , A61K38/00 , A61K38/26 , A61K39/3955 , A61K47/60 , A61P3/04 , A61P3/10 , A61P9/10 , A61P9/12 , C07K14/47 , C07K16/283
摘要： A a triple agonist having activities to all of glucagon, GLP-1, and GIP receptors is disclosed. Uses of the triple agonist are disclosed.
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公开(公告)号：US10513550B2
公开(公告)日：2019-12-24
申请号：US15539238
申请日：2015-12-30
发明人： Sung Youb Jung , Young Jin Park , Jong Suk Lee , Jae Hyuk Choi , Chang Ki Lim , Se Chang Kwon
IPC分类号： A61K38/26 , C07K14/605 , A61K45/06 , A61K38/00
摘要： The present invention relates to a novel peptide of a glucagon derivative and a composition for preventing or treating obesity comprising the peptide as an active ingredient. The glucagon derivative according to the present invention shows a more excellent activating effect with regard to both glucagon-like peptide-1 receptors and glucagon receptors compared to native glucagon, and thus can be widely used as an effective agent for treating obesity.
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公开(公告)号：US10370426B2
公开(公告)日：2019-08-06
申请号：US16023994
申请日：2018-06-29
发明人： Euh Lim Oh , Jong Suk Lee , Young Jin Park , Chang Ki Lim , Sung Youb Jung , Se Chang Kwon
IPC分类号： C07K14/00 , C07K14/605 , A61K38/26 , A61P3/04 , A61P3/10 , A61K39/395 , C07K14/47 , C07K16/28 , A61K47/60 , A61P9/10 , A61P9/12 , A61K38/00
摘要： The present invention relates to a triple agonist having activities to all of glucagon, GLP-1, and GIP receptors and uses thereof.
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公开(公告)号：US20190153060A1
公开(公告)日：2019-05-23
申请号：US16263469
申请日：2019-01-31
发明人： Euh Lim OH , Jong Suk Lee , Young Jin Park , Chang Ki Lim , Sung Youb Jung , Se Chang Kwon
IPC分类号： C07K14/605 , C07K16/28 , A61P3/10 , A61P3/04 , C07K14/47 , A61K38/26 , A61K39/395
摘要： A long-acting conjugate of a triple agonist which has activities to all of glucagon, GLP-1, and GIP receptors and uses thereof.
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