公开(公告)号：US20180305398A1

公开(公告)日：2018-10-25

申请号：US15767756

申请日：2016-10-12

申请人： HETERO RESEARCH FOUNDATION

发明人： Parthasaradhi Reddy BANDI ,  Rathnakar Reddy KURA ,  David Krupadanam GAZULA LEVI ,  Panduranga Reddy ADULLA ,  Bhaskar Reddy KASIREDDY ,  Carl Thomas Wild ,  David Eugene Martin ,  Theodore John Nitz

IPC分类号： C07J53/00 ,  A61P31/18

摘要： The present invention relates to C-3 novel triterpenone with C-28 urea derivatives of formula (I); or pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutically acceptable hydrates, tautomers, stereoisomers, prodrugs, compositions or combination thereof, wherein R1, R2, R3, W, J and X are as defined herein. The present invention also relates to pharmaceutical compositions comprising compounds of formula (I) useful for the treatment of viral diseases and particularly HIV mediated diseases.

公开(公告)号：US20180237472A1

公开(公告)日：2018-08-23

申请号：US15558677

申请日：2016-03-12

申请人： HETERO RESEARCH FOUNDATION

发明人： Parthasaradhi Reddy BANDI ,  Rathnakar Reddy KURA ,  David Krupadanam GAZULA LEVI ,  Panduranga Reddy ADULLA ,  Eswara Rao BAMMIDI ,  Bhaskar Reddy KASIREDDY ,  Sudhakar NEELA ,  Carl Thomas WILD ,  David Eugene MARTIN ,  Theodore John NITZ

IPC分类号： C07J63/00 ,  A61P31/18

CPC分类号： C07J63/008 ,  A61P31/18

摘要： The invention relates to C-3 novel triterpenone with C-28 amide derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases (formula 1).