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公开(公告)号：US10934251B2
公开(公告)日：2021-03-02
申请号：US16797498
申请日：2020-02-21
IPC分类号： C07C231/02 , C07D211/58 , C07C231/12 , C07C67/293 , C07C69/157 , C07C51/367 , C07C62/32
摘要： The present invention relates to a process for preparing Lomitapide or its pharmaceutically acceptable salt thereof having high purity with acceptable levels of impurities.
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公开(公告)号：US20180148412A1
公开(公告)日：2018-05-31
申请号：US15882317
申请日：2018-01-29
发明人： Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Dsari Muralidhara Reddy , Mogili Narsingam , Bandi Vamsi Krishna
IPC分类号： C07D213/82 , C07D213/79 , C07C231/02 , C07D213/14
CPC分类号： C07D213/82 , C07C231/02 , C07D213/14 , C07D213/69 , C07D213/79 , C07D213/80 , C07D213/81 , C07D309/40 , C07D498/12
摘要： The present invention provides a novel processes for preparation of methyl 3-(benzyloxy)-5-(2,4-difluorobenzylcarbamoyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyiridine-2-carboxylate using novel intermediates.
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公开(公告)号：US20170334858A1
公开(公告)日：2017-11-23
申请号：US14968088
申请日：2015-12-14
发明人： Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Dasari Muralidhara Reddy , Mogili Narsingam , Bandi Vamsi Krishna
IPC分类号： C07D213/82 , C07C231/02 , C07D213/14 , C07D213/79
CPC分类号： C07D213/82 , C07C231/02 , C07D213/14 , C07D213/69 , C07D213/79 , C07D213/80 , C07D213/81 , C07D309/40 , C07D498/12
摘要： The present invention provides a novel processes for preparation of methyl 3-(benzyloxy)-5-(2,4-difluorobenzylcarbamoyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyiridine-2-carboxylate using novel intermediates.
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公开(公告)号：US20170304451A1
公开(公告)日：2017-10-26
申请号：US15645237
申请日：2017-07-10
IPC分类号： A61K47/22 , A61K31/4184 , A61K9/08 , A61K47/10 , A61K9/00
CPC分类号： A61K47/22 , A61K9/0019 , A61K9/08 , A61K31/4184 , A61K47/10
摘要： Described herein are parenteral compositions of bendamustine. More particularly, parenteral compositions of bendamustine are in the form of solution.
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公开(公告)号：US09783542B2
公开(公告)日：2017-10-10
申请号：US14436962
申请日：2013-11-01
发明人： Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Dasari Muralidhara Reddy , Katham Srinivasa Reddy , Bandi Vamsi Krishna
IPC分类号： C07C67/52 , C07C67/343 , C07D475/08
CPC分类号： C07D475/08 , C07C67/343 , C07C67/52 , C07C69/76
摘要： The present invention provides a novel process for the purification of alpha-propargylhomoterephthalic acid dimethyl ester substantially free of homoterephthalic acid dimethyl ester. The present invention also provides a novel process for the purification of pralatrexate.
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公开(公告)号：US20170119678A1
公开(公告)日：2017-05-04
申请号：US15320080
申请日：2015-06-08
IPC分类号： A61K9/48 , A61K9/20 , A61K31/404
CPC分类号： A61K9/4808 , A61K9/2018 , A61K9/2027 , A61K9/2031 , A61K31/403 , A61K31/404
摘要： The present invention relates to solid oral dosage forms of carvedilol phosphate. More specifically, the present invention relates to extended release compositions of carvedilol phosphate and process for their preparation.
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公开(公告)号：US09637516B2
公开(公告)日：2017-05-02
申请号：US14758309
申请日：2013-12-26
发明人： Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Lanka Vl Subrahmanyam , Gazula Levi David Krupadanam , Mukkera Venkati , Neela Sudhakar , Kallem Srinivas Reddy
CPC分类号： C07J53/002 , C07J63/008
摘要： The invention relates to novel betulinic acid derivatives and related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases.
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公开(公告)号：US20170088537A1
公开(公告)日：2017-03-30
申请号：US14872743
申请日：2015-10-01
发明人： Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Dasari Muralidhara Reddy , Matta Ramakrishna Krishna Reddy , Bandi Vamsi Krishna
IPC分类号： C07D401/04
CPC分类号： C07D401/04 , C07B2200/13
摘要： The present invention provides a novel process for the preparation of pomalidomide crystalline Form I. The present invention also provides a process for the purification of pomalidomide.
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公开(公告)号：US20170051009A1
公开(公告)日：2017-02-23
申请号：US14754217
申请日：2015-06-29
发明人： Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Dasari Muralidhara Reddy , Katham Srinivasa Reddy , Bandi Vamshi Krishna
CPC分类号： C07J43/003 , C07J1/0011 , C07J31/006
摘要： The present invention provides a novel process for the preparation of abiraterone. The present invention also provides a novel process for the preparation of abiraterone acetate.
摘要翻译： 本发明提供了一种制备阿比特龙的新方法。 本发明还提供了制备醋酸阿维酮酮的新方法。
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公开(公告)号：US20160251313A1
公开(公告)日：2016-09-01
申请号：US15026694
申请日：2014-09-29
发明人： Bandi PARTHASARADHI REDDY , Kura RATHNAKAR REDDY , Dasari MURALIDHARA REDDY , Thungathurthy SRINIVASA RAO , Bandi VAMSI KRISHNA
IPC分类号： C07D213/81
CPC分类号： C07D213/81 , C07B2200/13
摘要： The present invention provides processes for the preparation of i) Regorafenib (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide, BAY 73-4506, Stivarga®) and its pharmaceutically acceptable salt thereof; ii) a crystalline solid of Regorafenib tosylate; iii) Regorafenib Polymorph I from Regorafenib tosylate, and iv) a pure 4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide from 4-amino-3-fluorophenol and 4-chloro-N-methylpicolinamide in the presence of potassium tert-butoxide.
摘要翻译： 本发明提供了制备i）雷卡非尼（4- [4 - （{[4-氯-3-（三氟甲基）苯基]氨基甲酰基}氨基）-3-氟苯氧基] -N-甲基吡啶-2-甲酰胺的方法， BAY 73-4506，Stivarga？）及其药学上可接受的盐; ii）瑞波非尼甲苯磺酸盐的结晶固体; iii）从罗非拉布甲苯磺酸盐获得的瑞考非非多晶型I，和iv）在钾存在下，由4-氨基-3-氟苯酚和4-氯-N-甲基吡啶酰胺制得纯的4-（4-氨基-3-氟苯氧基）-N-甲基吡啶酰胺 叔丁醇盐。
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