-
公开(公告)号：US11412930B2
公开(公告)日：2022-08-16
申请号：US16533133
申请日：2019-08-06
Applicant: HI LLC
Inventor： Jamu Alford , Adam Marblestone , Ivo Vellekoop , Daniel Sobek , Michael Henninger , Brian Robinson , Yuecheng Shen , Roarke Horstmeyer
Abstract: An optical measurement system comprising an optical source configured for delivering sample light in an anatomical structure, such that the sample light is scattered by the anatomical structure, resulting in physiological-encoded signal light that exits the anatomical structure, an optical detector configured for detecting the physiological-encoded signal light, and a processor configured for acquiring a TOF profile derived from the physiological-encoded signal light, the initial TOF profile having an initial contrast-to-noise ratio (CNR) between a plurality of states of a physiological activity in the anatomical structure. The processor is further configured for applying one or more weighting functions to the initial TOF profile to generate a weighted TOF profile having a subsequent CNR greater than the initial CNR between the plurality of states of the physiological activity. The processor is further configured for processing the weighted TOF profile, and identifying one of the plurality of states of the physiological activity.
-
公开(公告)号：US12064208B2
公开(公告)日：2024-08-20
申请号：US17663992
申请日：2022-05-18
Applicant: HI LLC
Inventor： Jamu Alford , Adam Marblestone , Ivo Vellekoop , Daniel Sobek , Michael Henninger , Brian Robinson , Yuecheng Shen , Roarke Horstmeyer
CPC classification number: A61B5/0004 , A61B5/0066 , A61B5/0084 , A61B5/0261
Abstract: An optical measurement system comprising an optical source configured for delivering sample light in an anatomical structure, such that the sample light is scattered by the anatomical structure, resulting in physiological-encoded signal light that exits the anatomical structure, an optical detector configured for detecting the physiological-encoded signal light, and a processor configured for acquiring a TOF profile derived from the physiological-encoded signal light, the initial TOF profile having an initial contrast-to-noise ratio (CNR) between a plurality of states of a physiological activity in the anatomical structure. The processor is further configured for applying one or more weighting functions to the initial TOF profile to generate a weighted TOF profile having a subsequent CNR greater than the initial CNR between the plurality of states of the physiological activity. The processor is further configured for processing the weighted TOF profile, and identifying one of the plurality of states of the physiological activity.
-
公开(公告)号：US20230301515A1
公开(公告)日：2023-09-28
申请号：US17663992
申请日：2023-05-18
Applicant: HI LLC
Inventor： Jamu Alford , Adam Marblestone , Ivo Vellekoop , Daniel Sobek , Michael Henninger , Brian Robinson , Yuecheng Shen , Roarke Horstmeyer
IPC: A61B5/00
CPC classification number: A61B5/0004 , A61B5/0084 , A61B5/0066 , A61B5/0261
Abstract: An optical measurement system comprising an optical source configured for delivering sample light in an anatomical structure, such that the sample light is scattered by the anatomical structure, resulting in physiological-encoded signal light that exits the anatomical structure, an optical detector configured for detecting the physiological-encoded signal light, and a processor configured for acquiring a TOF profile derived from the physiological-encoded signal light, the initial TOF profile having an initial contrast-to-noise ratio (CNR) between a plurality of states of a physiological activity in the anatomical structure. The processor is further configured for applying one or more weighting functions to the initial TOF profile to generate a weighted TOF profile having a subsequent CNR greater than the initial CNR between the plurality of states of the physiological activity. The processor is further configured for processing the weighted TOF profile, and identifying one of the plurality of states of the physiological activity.
-
公开(公告)号：US20200060542A1
公开(公告)日：2020-02-27
申请号：US16533133
申请日：2019-08-06
Applicant: HI LLC
Inventor： Jamu Alford , Adam Marblestone , Ivo Vellekoop , Daniel Sobek , Michael Henninger , Brian Robinson , Yuecheng Shen , Roarke Horstmeyer
IPC: A61B5/00
Abstract: An optical measurement system comprising an optical source configured for delivering sample light in an anatomical structure, such that the sample light is scattered by the anatomical structure, resulting in physiological-encoded signal light that exits the anatomical structure, an optical detector configured for detecting the physiological-encoded signal light, and a processor configured for acquiring a TOF profile derived from the physiological-encoded signal light, the initial TOF profile having an initial contrast-to-noise ratio (CNR) between a plurality of states of a physiological activity in the anatomical structure. The processor is further configured for applying one or more weighting functions to the initial TOF profile to generate a weighted TOF profile having a subsequent CNR greater than the initial CNR between the plurality of states of the physiological activity. The processor is further configured for processing the weighted TOF profile, and identifying one of the plurality of states of the physiological activity.
-
-
-
Search Results
4
records
(took 0.012 seconds)
