公开(公告)号：US20180289630A1

公开(公告)日：2018-10-11

申请号：US15769393

申请日：2016-10-24

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Atsushi SONOBE ,  Akio TAKEUCHI ,  Yasunori TAKADA

IPC: A61K9/70 ,  A61K31/4468 ,  A61K47/22 ,  A61K47/02 ,  A61K47/14 ,  A61K47/44

CPC classification number: A61K9/7053 ,  A61K9/703 ,  A61K9/7069 ,  A61K31/4468 ,  A61K47/02 ,  A61K47/14 ,  A61K47/20 ,  A61K47/22 ,  A61K47/44

Abstract: A patch comprises a backing and an adhesive layer laminated on at least one surface of the backing, in which the adhesive layer contains at least one selected from the group consisting of fentanyl and salts thereof, and contains an adhesive base material and an antioxidant having a sulfur atom in its molecule.

公开(公告)号：US20220142940A1

公开(公告)日：2022-05-12

申请号：US17433289

申请日：2020-02-21

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Naoto KAMAKURA ,  Akio TAKEUCHI ,  Hisakazu KURITA

IPC: A61K9/70 ,  A61K47/20

Abstract: The present invention provides a transdermal patch comprising an adhesive layer on a backing, wherein the adhesive layer comprises a drug, DMSO, and an adhesive base, and the adhesive base comprises a styrene-based thermoplastic elastomer having a triblock content of 35% to 65%.

公开(公告)号：US20190216746A1

公开(公告)日：2019-07-18

申请号：US16331269

申请日：2017-10-10

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Takao KUROKAWA ,  Akio TAKEUCHI

IPC: A61K9/70 ,  A61K31/216 ,  A61K47/28

CPC classification number: A61K9/7053 ,  A61K9/70 ,  A61K31/216 ,  A61K47/28 ,  A61K47/32 ,  A61K47/34 ,  A61P13/10

Abstract: An oxybutynin-containing transdermal absorption preparation includes a support layer that is formed of a base fabric and has water repellency in at least a part thereof, and an adhesive layer laminated on one side of the support layer, in which the adhesive layer includes an adhesive composition containing oxybutynin or a pharmaceutically acceptable salt thereof, cholesterols, and a rubber adhesive base. The oxybutynin may be oxybutynin hydrochloride. A portion having the water repellency may be formed by a fluorine-containing compound. The base fabric may be a knitted fabric.