公开(公告)号：US10086183B2

公开(公告)日：2018-10-02

申请号：US15032709

申请日：2014-11-04

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Shunsuke Arami ,  Shinpei Nishimura ,  Seiji Tokumoto ,  Makoto Ogura

IPC: A61M37/00

Abstract: An applicator is configured to transfer an active ingredient into a body through skin by a puncture in the skin with microneedles. The applicator includes a piston plate that is provided with a first protrusion part and second protrusion parts on a lower surface side of a main body of the piston plate. The microneedles are provided on a surface of the first protrusion part. The second protrusion parts are provided in a periphery of the first protrusion part while spaced apart from the first protrusion part.

公开(公告)号：USD778434S1

公开(公告)日：2017-02-07

申请号：US29500072

申请日：2014-08-21

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Designer： Shunsuke Arami ,  Makoto Ogura

公开(公告)号：US09913970B2

公开(公告)日：2018-03-13

申请号：US14654029

申请日：2013-11-27

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Shunsuke Arami ,  Makoto Ogura ,  Seiji Tokumoto

IPC: A61M37/00 ,  A61K9/00 ,  A61M5/145 ,  A61M5/158

CPC classification number: A61M37/0015 ,  A61K9/0021 ,  A61M5/1454 ,  A61M2005/14506 ,  A61M2005/1585 ,  A61M2037/0023 ,  A61M2037/0046

Abstract: An applicator includes a piston plate, a non-linear coil spring, a casing, a lock means and a release means. The casing includes a tubular main body part that houses therein the piston plate and the non-linear coil spring, and a cover part that is arranged on one end side of the main body part. The cover part and the piston plate sandwich the non-linear coil spring there between. The lock means locks the piston plate with the casing such that the piston plate is held at a retraction position thereof on the cover part side in a state where the cover part and the piston plate compress the non-linear coil spring. The release means releases a locked state where the piston plate is locked with the casing by the lock means and where the cover part and the piston plate compress the non-linear coil spring.

公开(公告)号：US20150057604A1

公开(公告)日：2015-02-26

申请号：US14390260

申请日：2013-04-02

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Shunsuke Arami ,  Makoto Ogura ,  Seiji Tokumoto

IPC: A61M37/00

CPC classification number: A61M37/0015 ,  A61M2037/0023 ,  A61M2037/0046 ,  A61M2037/0053 ,  A61M2207/00 ,  Y10T29/49826

Abstract: A puncture device is a device for transferring an active ingredient into a body through a skin by piercing the skin with a microneedle. The puncture device comprises a tubular housing, a piston slidably arranged within the housing and having a main surface intersecting a sliding direction, and a nonlinear coil spring arranged within the housing and providing the piston with a biasing force. A plurality of microneedles are arranged on the main surface side.

Abstract translation: 穿刺装置是通过用微针刺穿皮肤通过皮肤将活性成分转移到身体中的装置。 穿刺装置包括管状壳体，可滑动地布置在壳体内并且具有与滑动方向相交的主表面的活塞和布置在壳体内的非线性螺旋弹簧，并为活塞提供偏置力。 多个微针布置在主表面侧。