公开(公告)号：US20220105060A1

公开(公告)日：2022-04-07

申请号：US17429683

申请日：2020-02-13

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Tatsuya SAKAKURA ,  Satoshi KIMURA ,  Seiichiro TSURU

IPC: A61K31/192 ,  A61K31/045 ,  A61K9/70 ,  A61K47/10

Abstract: The present invention provides a gel patch having a paste layer on a support, wherein the paste layer comprising ketoprofen or a pharmaceutically acceptable salt thereof, propylene glycol, 1-menthol, and water, wherein the mass of propylene glycol in the paste layer is 3-fold the mass of ketoprofen or less, and wherein the content of 1-menthol based on a total mass of the paste layer is 0.1 to 0.5 mass %.

公开(公告)号：US20240139119A1

公开(公告)日：2024-05-02

申请号：US18278279

申请日：2022-02-18

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Hisakazu KURITA ,  Naoto KAMAKURA ,  Tatsuya SAKAKURA

IPC: A61K9/70 ,  A61K31/196

CPC classification number: A61K9/7053 ,  A61K31/196

Abstract: A diclofenac-containing patch package product, in which a diclofenac-containing patch, including an adhesive layer containing diclofenac sodium as a drug and dimethyl sulfoxide as a solvent, and a backing layer, is sealed in a packaging bag,



the packaging bag being formed of a laminate at least comprising:
an innermost layer composed of at least one selected from the group consisting of polyethylene terephthalate and cycloolefin polymer;
an oxygen barrier layer arranged outside the innermost layer; and
an outer layer arranged outside the oxygen barrier layer.