公开(公告)号：US3661966A

公开(公告)日：1972-05-09

申请号：US3661966D

申请日：1969-08-04

Applicant: HOECHST AG

Inventor： BARTMANN WILHELM ,  DUWEL DIETER ,  GEORGI VOLKMAR ,  WOLF ERHARD ,  BEERMANN CLAUS ,  LANDAUER FRANZ

IPC: A61K31/14 ,  C07C233/00 ,  C07C125/06

CPC classification number: A61K31/14 ,  C07C233/00

Abstract: BIS-AMMONIUM COMPOUNDS OF THE FORMULA

R1-OC-N(-CH2-N(+)(-R2)(-R4)-R3))2 2X(-)

WHEREIN R1 IS ALKYL HAVING 1 TO 6 C-ATOMS, ALKOXY HAVING 1 TO 25 CARBON ATOMS, ALKENYOXY HAVING 3 TO 18 C-ATOMS, CYCLOALKOXY HAVING 4 TO 8 C-ATOMS, CYCLOALKYLALKOXY OR ALCKYLCYCLOALKOXY EACH HAVING 5 TO 8 C-ATOMS, AND HALOGENO-ALKOXY OR ALKOXYALKOXY EACH HAVING 1 TO 6 C-ATOMS, R2 IS ALKYL HAVING 1 TO 3 C-ATOMS, R3 IS ALKYL HAVING 1 TO 25 C-ATOMS, ALKENYL HAVING 3 TO 18 C-ATOMS, CYCLOALKYL HAVING 4 TO 8 C-ATOMS OR PHENALKYL HAVING 1 TO 2 C-ATOMS IN THE ALKYLENE RADICAL AND OPTIONALLY ONE CHLORINE ATOM OR A NITRO GROUP IN THE PHENYL NUCLEUS, R4 IS ALKYL HAVING 6 TO 25 C-ATOMS OR ALKENYL HAVING 5 TO 25 C-ATOMS, AND X- IS AN ANION OF A NON-TOXIC ACID AND A PROCESS FOR PREPARING THEM ARE DESCRIBED. THE COMPOUNDS HAVE VALUABLE ENTHELMINTIC PROPERTIES.

公开(公告)号：US3992538A

公开(公告)日：1976-11-16

申请号：US58818675

申请日：1975-06-19

Applicant: HOECHST AG

Inventor： TEUFEL HERMANN ,  BARTMANN WILHELM ,  BECK GERHARD ,  GRANZER ERNOLD

IPC: A61K31/15 ,  A61K20060101 ,  C07C20060101 ,  C07C67/00 ,  C07C239/00 ,  C07C251/66

CPC classification number: C07D417/04