公开(公告)号：US10710968B2

公开(公告)日：2020-07-14

申请号：US16069546

申请日：2017-01-12

Applicant: Hadasit Medical Research Services and Development Ltd.

Inventor： Eyal Yosef Mishani ,  Ofer Shamni ,  Galith Rachel Abourbeh-Gofrit

IPC: A61K51/00 ,  A61M36/14 ,  C07D239/94 ,  A61K45/06 ,  A61P35/00 ,  A61K51/04 ,  C07B59/00 ,  C12Q1/6886

Abstract: Radiolabeled compounds which are erlotinib analogs that feature a radioactive halogen and processes of preparing same are disclosed. Uses of these radiolabeled compounds in radioimaging, for identifying and monitoring a level, distribution and/or mutational status of deregulated EGFR, and/or in radiotherapy, are also disclosed.