Mite allergen
    2.
    发明授权
    Mite allergen 有权
    螨过敏原

    公开(公告)号:US08647630B2

    公开(公告)日:2014-02-11

    申请号:US13230448

    申请日:2011-09-12

    摘要: A safe and efficient recombinant mite allergen is provided as a therapeutic agent or a diagnostic agent for mite allergic diseases, which contains no anaphylaxis-inducing impurities. The following recombinant protein (a) or (b) is provided: (a) a protein comprising the amino acid sequence represented by SEQ ID NO: 2 or 35; or (b) a protein comprising an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 2 or 35 by deletion, substitution, or addition of one or several amino acids and having mite allergen activity.

    摘要翻译: 提供安全有效的重组螨变应原作为不含过敏反应性杂质的螨过敏性疾病的治疗剂或诊断剂。 提供以下重组蛋白(a)或(b):(a)包含SEQ ID NO:2或35所示的氨基酸序列的蛋白质; 或(b)通过缺失,取代或添加一个或几个氨基酸并具有螨变应原活性的蛋白质,其包含由SEQ ID NO:2或35所示的氨基酸序列衍生的氨基酸序列。

    Mite allergen
    4.
    发明授权
    Mite allergen 有权
    螨过敏原

    公开(公告)号:US08075898B2

    公开(公告)日:2011-12-13

    申请号:US11547850

    申请日:2005-04-07

    IPC分类号: A61K39/00 A61K39/35 A61K39/36

    摘要: A safe and efficient recombinant mite allergen is provided as a therapeutic agent or a diagnostic agent for mite allergic diseases, which contains no anaphylaxis-inducing impurities. The following recombinant protein (a) or (b) is provided: (a) a protein comprising the amino acid sequence represented by SEQ ID NO: 2 or 35; or (b) a protein comprising an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 2 or 35 by deletion, substitution, or addition of one or several amino acids and having mite allergen activity.

    摘要翻译: 提供安全有效的重组螨变应原作为不含过敏反应性杂质的螨过敏性疾病的治疗剂或诊断剂。 提供以下重组蛋白(a)或(b):(a)包含SEQ ID NO:2或35所示的氨基酸序列的蛋白质; 或(b)通过缺失,取代或添加一个或几个氨基酸并具有螨变应原活性的蛋白质,其包含由SEQ ID NO:2或35所示的氨基酸序列衍生的氨基酸序列。