公开(公告)号：US09757392B2

公开(公告)日：2017-09-12

申请号：US12415205

申请日：2009-03-31

Applicant: Hang-Ching Lin ,  Tsu-Chung Chang ,  Wen-Liang Chang ,  Yi-Yang Song

Inventor： Hang-Ching Lin ,  Tsu-Chung Chang ,  Wen-Liang Chang ,  Yi-Yang Song

IPC: A61K9/00 ,  A61K31/56 ,  A61K31/575 ,  A61K9/48 ,  A61K36/076 ,  A61K45/06

CPC classification number: A61K31/575 ,  A61K9/485 ,  A61K9/4866 ,  A61K36/076 ,  A61K45/06 ,  A61K2300/00

Abstract: The present invention discloses a novel use of a lanostane having the following formula (I) in enhancing uptake of nutrients: wherein R1 is either H or CH3; R2 is OCOCH3, ═O or OH; R3 is H or OH; R4 is —C(═CH2)—C(CH3)2Ra, in which Ra is H or OH, or —CH═C(CH3)—Rb, in which Rb is CH3 or CH2OH; R5 is H or OH; and R6 is CH3 or CH2OH.

公开(公告)号：US20120196816A1

公开(公告)日：2012-08-02

申请号：US13444765

申请日：2012-04-11

Applicant: Hang-Ching Lin ,  Wen-Liang Chang ,  Tsu-Chung Chang ,  Hsiou-Yu Ding ,  Tian Shung Wu

Inventor： Hang-Ching Lin ,  Wen-Liang Chang ,  Tsu-Chung Chang ,  Hsiou-Yu Ding ,  Tian Shung Wu

IPC: A61K31/704 ,  A61P3/00

CPC classification number: A61K31/704 ,  A61K36/481 ,  Y10S514/909 ,  Y10S514/923

Abstract: The present application relates to a method for enhancing absorption of a nutrient in a subject in need thereof with an effective amount of an isolated astragaloside compound.

Abstract translation: 本申请涉及一种用有效量的分离的黄芪甲苷化合物增强有需要的受试者的营养素吸收的方法。

公开(公告)号：US07959952B2

公开(公告)日：2011-06-14

申请号：US11469659

申请日：2006-09-01

Applicant: Wen-Liang Chang ,  Tsu-Chung Chang ,  Hang-Ching Lin ,  Yuan Yang

Inventor： Wen-Liang Chang ,  Tsu-Chung Chang ,  Hang-Ching Lin ,  Yuan Yang

IPC: A61K36/00 ,  A61K36/481 ,  A61K8/97 ,  A61K36/48

CPC classification number: A61K36/481 ,  A61K8/63 ,  A61K8/97 ,  A61K31/56 ,  A61K31/704 ,  A61K2800/92 ,  A61Q19/08

Abstract: A method for skin care includes administering the water insoluble fraction of Astragalus membranaceus, or astragaloside compounds thereof to a subject in need thereof at an effective amount for improving skin texture, reducing wrinkles, UV protection, and/or providing an anti-aging effect.

Abstract translation: 一种皮肤护理方法，其特征在于，向有需要的受试者施用黄芪的水不溶性部分或黄芪甲苷化合物，以改善皮肤纹理，减少皱纹，紫外线防护和/或提供抗衰老作用的有效量。

公开(公告)号：US20120232041A1

公开(公告)日：2012-09-13

申请号：US13383261

申请日：2009-07-10

Applicant: Muh-Hwan Su ,  Jing Jing Justine Tang ,  Hang-Ching Lin

Inventor： Muh-Hwan Su ,  Jing Jing Justine Tang ,  Hang-Ching Lin

IPC: A61K31/353 ,  A61P9/10 ,  A61K31/616

CPC classification number: A61K31/353 ,  A61K36/82 ,  A61K45/06 ,  A61K2300/00

Abstract: The present invention provides a pharmaceutical composition for the treatment and prophylaxis of angina and myocardial infarction, wherein a combination of a tea extract (catechins) and an antianginal drug are proved therapeutically potent in treating angina and mycocardial infarction induced from myocardial ischemia. The present invention also provides a use of a tea extract (catechins) in treating and preventing angina.

Abstract translation: 本发明提供了用于治疗和预防心绞痛和心肌梗死的药物组合物，其中茶提取物（儿茶素）和抗心绞痛药物的组合被证明在治疗心肌缺血诱导的心绞痛和心肌梗塞中具有治疗作用。 本发明还提供茶提取物（儿茶素类）治疗和预防心绞痛的用途。

公开(公告)号：US20090247496A1

公开(公告)日：2009-10-01

申请号：US12415205

申请日：2009-03-31

Applicant: Hang-Ching Lin ,  Tsu-Chung Chang ,  Wen-Liang Chang ,  Yi-Yang Song

Inventor： Hang-Ching Lin ,  Tsu-Chung Chang ,  Wen-Liang Chang ,  Yi-Yang Song

IPC: A61K31/575 ,  A61P3/00

CPC classification number: A61K31/575 ,  A61K9/485 ,  A61K9/4866 ,  A61K36/076 ,  A61K45/06 ,  A61K2300/00

Abstract: The present invention discloses a novel use of a lanostane having the following formula (I) in enhancing uptake of nutrients: wherein R1 is either H or CH3; R2 is OCOCH3, ═O or OH; R3 is H or OH; R4 is —C(═CH2)—C(CH3)2Ra, in which Ra is H or OH, or —CH═C(CH3)—Rb, in which Rb is CH3 or CH2OH; R5 is H or OH; and R6 is CH3 or CH2OH.

Abstract translation: 本发明公开了具有下式（I）的羊毛甾烷醇在增加营养素摄取中的新用途：其中R1是H或CH3; R2是OCOCH3，-O或OH; R3是H或OH; R4是-C（-CH2）-C（CH3）2Ra，其中Ra是H或OH，或-CH-C（CH3）-Rb，其中Rb是CH3或CH2OH; R5是H或OH; 并且R 6是CH 3或CH 2 OH。

公开(公告)号：US20100298283A1

公开(公告)日：2010-11-25

申请号：US12838545

申请日：2010-07-19

Applicant: Hang-Ching Lin ,  Jerming Tseng ,  Hsiou-Yu Ding ,  Wen-Liang Chang ,  Chien-Lian Chao ,  Hsin-Wen Huang

Inventor： Hang-Ching Lin ,  Jerming Tseng ,  Hsiou-Yu Ding ,  Wen-Liang Chang ,  Chien-Lian Chao ,  Hsin-Wen Huang

IPC: A61K31/575 ,  A61P37/00

CPC classification number: A61K39/00 ,  A61K31/56 ,  A61K31/575 ,  A61K36/076

Abstract: A pharmaceutical composition is used to enhance immunity of the human body. The composition contains potent components of lanostane compounds. A method is devised to obtain an extract from metabolite, sclerotium, or fermentation product of Poria cocos (Schw) Wolf. The extract contains 5-60% of the lanostane compounds by weight of the extract. The extract is devoid of secolanostane capable of inhibiting immunity development.

Abstract translation: 药物组合物用于增强人体的免疫力。 该组合物含有羊毛甾烷化合物的有效成分。 设计出一种获得茯苓（Schw）狼的代谢物，菌核或发酵产物的提取物的方法。 提取物含有按重量计提取的5-60％的羊毛甾醇化合物。 该提取物没有能够抑制免疫发育的西裤筒。

公开(公告)号：US20080057010A1

公开(公告)日：2008-03-06

申请号：US11469659

申请日：2006-09-01

Applicant: Wen-Liang Chang ,  Tsu-Chung Chang ,  Hang-Ching Lin ,  Yuan Yang

Inventor： Wen-Liang Chang ,  Tsu-Chung Chang ,  Hang-Ching Lin ,  Yuan Yang

IPC: A61K8/97 ,  A61K36/48 ,  A61K31/704 ,  A61K31/56

CPC classification number: A61K36/481 ,  A61K8/63 ,  A61K8/97 ,  A61K31/56 ,  A61K31/704 ,  A61K2800/92 ,  A61Q19/08

Abstract: The present invention provides a method for skin care comprising administering an the water insoluble fraction of Astragalus membranaceus, or astragaloside compounds to a subject in need thereof at an effective amount for improving skin texture, reducing wrinkles, UV protection, and anti-aging effect.

Abstract translation: 本发明提供了一种皮肤护理方法，其包括向有需要的受试者施用黄芪的水不溶性部分或黄芪苷化合物，以有效量施用以改善皮肤纹理，减少皱纹，防紫外线和抗衰老作用。

公开(公告)号：US20050256209A1

公开(公告)日：2005-11-17

申请号：US11126234

申请日：2005-05-11

Applicant: Hang-Ching Lin ,  Hsiou-Yu Ding ,  Wen-Liang Chang ,  Chien-Liang Chao ,  Hsin-Wen Huang ,  Chin-Liang Lin

Inventor： Hang-Ching Lin ,  Hsiou-Yu Ding ,  Wen-Liang Chang ,  Chien-Liang Chao ,  Hsin-Wen Huang ,  Chin-Liang Lin

IPC: A61P19/10 ,  A61K31/05 ,  A61P35/00

CPC classification number: A61K31/05

Abstract: The present invention discloses a novel use of bakuchiol or an extract containing bakuchiol in preventing or treating a woman suffering osteoporosis. An embodiment of this novel use is a pharmaceutical composition containing bakuchiol or an extract containing bakuchiol, which can be in the dosage forms of topical use, oral administration, injection or sustained release. The present invention also discloses a novel use of bakuchiol or an extract containing bakuchiol in preventing or treating a woman suffering breast cancer.

Abstract translation: 本发明公开了一种用于预防或治疗患有骨质疏松症的女性的bakuchiol或含有bakuchiol的提取物的新用途。 这种新用途的一个实施方案是含有bakuchiol或含有bakuchiol的提取物的药物组合物，其可以是局部使用，口服给药，注射或持续释放的剂型。 本发明还公开了一种新颖的使用bakuchiol或含有bakuchiol的提取物来预防或治疗患有乳腺癌的女性。

公开(公告)号：US08658629B2

公开(公告)日：2014-02-25

申请号：US12771777

申请日：2010-04-30

Applicant: Hang-Ching Lin

Inventor： Hang-Ching Lin

IPC: A61K31/56

CPC classification number: A61K9/1652 ,  A61K9/4866 ,  A61K31/575 ,  A61K36/076

Abstract: A pharmaceutical composition for treating cachexia, and in particular for treating cancer cachexia. The composition contains a lanostane compound as a potent component. A suitable source of the lanostane compound is a Poria extract from metabolite, sclerotium, or fermentation product of Poria cocos (Schw) Wolf. The Poria extract contains 1-60% of the lanostane compounds by weight of the extract, and is devoid of secolanostane.

Abstract translation: 用于治疗恶病质，特别是用于治疗恶病质的药物组合物。 该组合物含有羊毛甾醇化合物作为有效成分。 羊毛甾烷化合物的合适来源是茯苓（Schw）狼的代谢物，菌核或发酵产物的茯苓提取物。 茯苓提取物含有1-60％的羊毛甾烷化合物，其重量为提取物，并且没有塞可安烷。

公开(公告)号：US08168596B2

公开(公告)日：2012-05-01

申请号：US12253779

申请日：2008-10-17

Applicant: Wen-Liang Chang ,  Tsu-Chung Chang ,  Hang-Ching Lin ,  Yuan Yang ,  Shu-Fen Huang

Inventor： Wen-Liang Chang ,  Tsu-Chung Chang ,  Hang-Ching Lin ,  Yuan Yang ,  Shu-Fen Huang

IPC: A61K31/56 ,  A01N45/00

CPC classification number: A61K31/704 ,  A61K9/0019

Abstract: A method of treating a disease associated with cartilage defect in a subject in need thereof by administering to the subject an effectively amount of a cycloartane compound of Formula (I).

Abstract translation: 一种通过向受试者施用有效量的式（I）的环加烷化合物来治疗有需要的受试者与软骨缺损相关的疾病的方法。