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1.发明授权Recombinant kinase from insect cells for the synthesis of nucleoside monophosphates 有权来自昆虫细胞的重组激酶用于合成核苷单磷酸公开(公告)号：US07625735B2
公开(公告)日：2009-12-01
申请号：US10680635
申请日：2003-10-07
CPC分类号： C12N9/1205
摘要： A recombinant Drosophila melanogaster deoxynucleoside kinase that remains stable during the synthesis of nucleoside monophosphate without the addition of stabilizing SH reagents or stabilizing proteins, and that accepts all four natural deoxynucleotides is provided. In addition, the invention concerns DNA sequences, vectors, transformed cells, a method for production of the recombinant kinase as well as its use for preparing nucleoside monophosphates.
摘要翻译： 提供了一种重组黑腹果蝇脱氧核苷激酶，其在合成核苷单磷酸酯期间保持稳定，而不添加稳定的SH试剂或稳定蛋白，并且接受所有四种天然脱氧核苷酸。 此外，本发明涉及DNA序列，载体，转化细胞，重组激酶的制备方法及其制备核苷单磷酸的用途。
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2.发明申请Deoxynucleoside kinase from insect cells for the synthesis of nucleoside monophosphates 有权来自昆虫细胞的脱氧核苷激酶用于合成核苷单磷酸酯公开(公告)号：US20060252131A1
公开(公告)日：2006-11-09
申请号：US10680635
申请日：2003-10-07
CPC分类号： C12N9/1205
摘要： Recombinant kinase remaining stable during the synthesis of necleoside monophosphate without the addition of stabilizing SH reagents, without stabilizing proteins and accepting all four natural deoxynucleotides, obtainable from insect cells such as e.g. Drosophila Melanogaster. In addition, the invention concerns DNA sequences, vectors, transformed cells, a method for production of the recombinant kinase as well as its use for preparing nucleoside monophosphates.
摘要翻译： 重组激酶在合成核苷酸单磷酸酯期间保持稳定，而不添加稳定的SH试剂，而不稳定蛋白质并接受可从昆虫细胞获得的所有四种天然脱氧核苷酸。 果蝇Melanogaster。 此外，本发明涉及DNA序列，载体，转化细胞，重组激酶的制备方法及其制备核苷单磷酸的用途。
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