公开(公告)号：US12259344B1

公开(公告)日：2025-03-25

申请号：US18809820

申请日：2024-08-20

Applicant: Harbin Institute of Technology

Inventor： Chenguang Liu ,  Jian Liu ,  Zhao Chen

IPC: G01N23/2255 ,  G01T1/20 ,  G01T1/29

Abstract: Provided is a living cell microbeam directional and quantitative irradiation imaging apparatus. The problem that qualitative analysis of the mechanism of action of biological cells irradiated cannot accurately study the mechanism of action of different irradiation doses on biological cells as the cell irradiation technology can be only used to perform qualitative irradiation on living biological cells is solved. The apparatus includes a vertical microbeam terminal, a living cell directional irradiation module, a wide-field microscopic module, a mode switching module, and a single-proton counting and radiation synchronous control module. The vertical microbeam terminal, the living cell directional irradiation module, the mode switching module and the wide-field microscopic module are sequentially matched, the mode switching module is connected to the single-proton counting and radiation synchronous control module, and the vertical microbeam terminal is matched with the single-proton counting and radiation synchronous control module.