公开(公告)号：US20060233838A1

公开(公告)日：2006-10-19

申请号：US11248552

申请日：2005-10-12

申请人： Harold Conkle ,  Joseph Schultz ,  Scott Blonigen ,  Fred Weber ,  David Kilanowski ,  Bruce Monzyk ,  Timothy Werner ,  Chad Cucksey ,  Hamish McArthur ,  Ted Tewksbury

发明人： Harold Conkle ,  Joseph Schultz ,  Scott Blonigen ,  Fred Weber ,  David Kilanowski ,  Bruce Monzyk ,  Timothy Werner ,  Chad Cucksey ,  Hamish McArthur ,  Ted Tewksbury

IPC分类号： A61K39/012 ,  C12N1/10

CPC分类号： A61K39/012 ,  C12N1/10 ,  Y10S435/947

摘要： A vaccine for in ovo vaccination against avian coccidiosis produced by a method including obtaining the coccidial oocysts from a fecal suspension, homogenizing the fecal suspension, separating the oocysts from the fecal debris by either salt flotation using sodium sulfate or gas flotation using air, sporulating the oocysts using hydrogen peroxide and air sparging, bleaching the sporulated oocysts, washing the bleached oocysts, concentrating the sterile washed oocysts and combining the concentrates of various species of coccidial oocysts, and producing a vaccine. The method in whole or in part can be applied to other kinds of encysted protozoa to produce vaccines for various types of animals.

摘要翻译： 一种用于通过包括从粪便悬浮液获得球虫卵囊，粪便悬浮液均质化，通过使用硫酸钠的盐浮选或使用空气气浮法从粪便碎片中分离卵囊的方法产生的针对禽类球虫病的疫苗的疫苗， 使用过氧化氢和空气喷射的卵囊，漂白孢子化的卵囊，洗涤漂白的卵囊，浓缩无菌洗涤的卵囊并组合各种球虫卵囊的浓缩物，并生产疫苗。 该方法全部或部分可应用于其他类型的包囊原生动物，以生产各种类型动物的疫苗。