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公开(公告)号:US4291019A
公开(公告)日:1981-09-22
申请号:US146141
申请日:1980-05-02
申请人: Harold W. Lupton , David E. Reed
发明人: Harold W. Lupton , David E. Reed
IPC分类号: A61K39/265
CPC分类号: A61K39/265 , A61K39/12 , A61K2039/552 , A61K2039/55566 , C12N2710/16734 , Y10S424/813
摘要: A vaccine for infectious bovine rhinotracheitis (IBR) is prepared by non-ionic detergent extraction of IBR virus infected cells. The extracted viral envelope protein can be prepared in injectable dose form by combination with an oil-type adjuvant. The vaccine produces a high level of antibody response, and is capable of eliminating virus shed for animals infected after immunization.
摘要翻译: 通过非离子洗涤剂提取IBR病毒感染细胞制备感染性牛鼻气管炎(IBR)疫苗。 提取的病毒包膜蛋白可以通过与油型佐剂组合而以可注射剂量形式制备。 该疫苗产生高水平的抗体应答,并且能够消除免疫后感染动物的病毒。