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公开(公告)号：US07871992B2
公开(公告)日：2011-01-18
申请号：US12137241
申请日：2008-06-11
申请人： Hassan Jomaa , Oliver Wolf , Boran Altincicek , Mathias Eberl , Martin Hintz , Ann-Kristin Kollas , Armin Reichenberg , Jochen Wiesner
发明人： Hassan Jomaa , Oliver Wolf , Boran Altincicek , Mathias Eberl , Martin Hintz , Ann-Kristin Kollas , Armin Reichenberg , Jochen Wiesner
IPC分类号： A61K31/66
CPC分类号： C07F9/65746 , A61K31/661 , C07F9/098 , C07F9/3821 , C07F9/3826 , C07F9/4025
摘要： The present invention describes organophosphorus compounds of general formula (I) their preparation and their uses in the activation of gamma/delta T-cells, in the screening of GcpE and LytB enzyme inhibitors and in the prophylaxis and treatment of diseases in humans and animals.
摘要翻译： 本发明描述了在筛选GcpE和LytB酶抑制剂以及预防和治疗人和动物疾病中通式（I）的有机磷化合物及其制备方法及其在γ/δT细胞活化中的用途。
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公开(公告)号：US20080249067A1
公开(公告)日：2008-10-09
申请号：US12137241
申请日：2008-06-11
申请人： Hassan Jomaa , Matthias Eberl , Boran Altincicek , Martin Hintz , Oliver Wolf , Ann-Kristin Kollas , Armin Reichenberg , Jochen Wiesner
发明人： Hassan Jomaa , Matthias Eberl , Boran Altincicek , Martin Hintz , Oliver Wolf , Ann-Kristin Kollas , Armin Reichenberg , Jochen Wiesner
IPC分类号： A61K31/665 , C07F9/655 , C07F9/06 , A61K31/663 , C12N5/06 , A01N57/16 , A61P33/00 , A01P13/00 , A61P31/04 , A61P31/12
CPC分类号： C07F9/65746 , A61K31/661 , C07F9/098 , C07F9/3821 , C07F9/3826 , C07F9/4025
摘要： The present invention describes organophosphorus compounds of general formula (I) their preparation and their uses in the activation of gamma/delta T-cells, in the screening of GcpE and LytB enzyme inhibitors and in the prophylaxis and treatment of diseases in humans and animals.
摘要翻译： 本发明描述了在筛选GcpE和LytB酶抑制剂以及预防和治疗人和动物疾病中通式（I）的有机磷化合物及其制备方法及其在γ/δT细胞活化中的用途。
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3.发明申请公开(公告)号：US20110112054A1
公开(公告)日：2011-05-12
申请号：US13007852
申请日：2011-01-17
申请人： Hassan Jomaa , Matthias Eberl , Boran Altincicek , Martin Hintz , Oliver Wolf , Ann-Kristin Kollas , Armin Reichenberg , Jochen Wiesner
发明人： Hassan Jomaa , Matthias Eberl , Boran Altincicek , Martin Hintz , Oliver Wolf , Ann-Kristin Kollas , Armin Reichenberg , Jochen Wiesner
IPC分类号： A61K31/6615 , A61P37/00 , A61P19/10 , A61P1/04 , A61P3/10 , A61P31/12 , A61P31/04 , A61P33/00 , A61P35/00 , A61K31/663
CPC分类号： C07F9/65746 , A61K31/661 , C07F9/098 , C07F9/3821 , C07F9/3826 , C07F9/4025
摘要： The present invention describes organophosphorus compounds of general formula (I) their preparation and their uses in the activation of gamma/delta T-cells, in the screening of GcpE and LytB enzyme inhibitors and in the prophylaxis and treatment of diseases in humans and animals.
摘要翻译： 本发明描述了在筛选GcpE和LytB酶抑制剂以及预防和治疗人和动物疾病中通式（I）的有机磷化合物及其制备方法及其在γ/δT细胞活化中的用途。
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公开(公告)号：US07399756B2
公开(公告)日：2008-07-15
申请号：US10484143
申请日：2002-07-18
申请人： Hassan Jomaa , Matthias Eberl , Boran Altincicek , Martin Hintz , Oliver Wolf , Ann-Kristin Kollas , Armin Reichenberg , Jochen Wiesner
发明人： Hassan Jomaa , Matthias Eberl , Boran Altincicek , Martin Hintz , Oliver Wolf , Ann-Kristin Kollas , Armin Reichenberg , Jochen Wiesner
CPC分类号： C07F9/65746 , A61K31/661 , C07F9/098 , C07F9/3821 , C07F9/3826 , C07F9/4025
摘要： The present invention describes organophosphorus compounds of general formula (I) their preparation and their uses in the activation of gamma/delta T-cells, in the screening of GcpE and LytB enzyme inhibitors and in the prophylaxis and treatment of diseases in humans and animals.
摘要翻译： 本发明描述了在筛选GcpE和LytB酶抑制剂以及预防和治疗人和动物疾病中通式（I）的有机磷化合物及其制备方法及其在γ/δT细胞活化中的用途。
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公开(公告)号：US20060030546A1
公开(公告)日：2006-02-09
申请号：US10484143
申请日：2002-07-18
申请人： Hassan Jomaa , Matthias Eberl , Boran Altincicek , Martin Hintz , Oliver Wolf , Ann-Kristin Kollas , Armin Reichenberg , Jochen Wiesner
发明人： Hassan Jomaa , Matthias Eberl , Boran Altincicek , Martin Hintz , Oliver Wolf , Ann-Kristin Kollas , Armin Reichenberg , Jochen Wiesner
IPC分类号： A61K31/663 , C07F9/547
CPC分类号： C07F9/65746 , A61K31/661 , C07F9/098 , C07F9/3821 , C07F9/3826 , C07F9/4025
摘要： The present invention describes organophosphorus compounds of general formula (I) their preparation and their uses in the activation of gamma/delta T-cells, in the screening of GcpE and LytB enzyme inhibitors and in the prophylaxis and treatment of diseases in humans and animals.
摘要翻译： 本发明描述了在筛选GcpE和LytB酶抑制剂以及预防和治疗人和动物疾病中通式（I）的有机磷化合物及其制备方法及其在γ/δT细胞活化中的用途。
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