专利检索 ap:("Hassan PAJOUHESH" OR "Hossein PAJOUHESH" OR "Yanbing DING" OR "Jason TAN" OR "Mike GRIMWOOD" OR "Francesco BELARDETTI" OR "Ramesh KAUL") AND inv:"Hossein PAJOUHESH" 第 1 页

1.

发明申请
BICYCLIC PYRIMIDINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS 失效
标题翻译：双相吡啶衍生物作为钙通道阻断剂

公开(公告)号：US20080280900A1

公开(公告)日：2008-11-13

申请号：US12118492

申请日：2008-05-09

申请人： Hassan PAJOUHESH , Hossein PAJOUHESH , Yanbing DING , Jason TAN , Mike GRIMWOOD , Francesco BELARDETTI , Ramesh KAUL

发明人： Hassan PAJOUHESH , Hossein PAJOUHESH , Yanbing DING , Jason TAN , Mike GRIMWOOD , Francesco BELARDETTI , Ramesh KAUL

IPC分类号： A61K31/5377 , A61K31/496 , A61P35/00

CPC分类号： A61K31/496 , A61K31/5377

摘要： Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted T-type calcium channel activity are disclosed. Specifically, a series of compounds containing thienopyrimidine or oxoquinazoline derivatives are disclosed of the general formula (1) or formula (2) where X is a linker and Y is an aromatic moiety or N(R5)(R6).

摘要翻译： 公开了有助于改善由不希望的钙通道活性，特别是不希望的T型钙通道活性表征的病症的方法和化合物。具体地说，通式（1）或式（2）公开了一系列含有噻吩并嘧啶或氧代喹唑啉衍生物的化合物，其中X为连接基，Y为芳族部分或N（R5）（R6）。