公开(公告)号：US20130217085A1

公开(公告)日：2013-08-22

申请号：US13812496

申请日：2011-01-13

申请人： He Huang ,  Qianqian Tong ,  Lujing Ren ,  Xiaojun Ji ,  Aihua Xiao ,  Ping Wei ,  Jiangying You ,  Liang Qu ,  Dongping Gong ,  Jiangyao Zhu

发明人： He Huang ,  Qianqian Tong ,  Lujing Ren ,  Xiaojun Ji ,  Aihua Xiao ,  Ping Wei ,  Jiangying You ,  Liang Qu ,  Dongping Gong ,  Jiangyao Zhu

IPC分类号： C12P7/64

CPC分类号： C12P7/6427

摘要： The present invention discloses a method of improving the fermentation yield of polyunsaturated fatty acids, in which Schizochytrium limacinum is used as production strain to produce polyunsaturated fatty acids (PUFA), and glycine betaine or trehalose is added to the fermentation medium. In the present invention, after Schizochytrium limacinum fermentation system is treated with exogenous glycine betaine, the yield of PUFA produced by fermentation with Schizochytrium limacinum can be greatly improved. The present invention significantly improves the yield of PUFA produced by microorganism, reduces the cost without harming the environment, and saves manpower and material resources by simple and effective regulation of fermentation, and thus the method is simple, convenient and cost-effective.

摘要翻译： 本发明公开了一种提高多不饱和脂肪酸的发酵产量的方法，其中使用裂殖壶菌作为生产菌株生产多不饱和脂肪酸（PUFA），将甘氨酸甜菜碱或海藻糖加入到发酵培养基中。 在本发明中，利用外源甘氨酸甜菜碱处理裂殖壶菌发酵系统后，可以大大提高利用裂殖壶菌发酵产生的PUFA产率。 本发明显着提高了微生物生产的PUFA的产量，降低了成本而不损害环境，通过简单有效的发酵调节节省了人力物力资源，方法简便，成本效益好。