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1.Dihydropyridine derivatives for use as human neutrophil elastase inhibitors 失效
标题翻译: 用作人嗜中性粒细胞弹性蛋白酶抑制剂的二氢吡啶衍生物公开(公告)号:US20070167406A1
公开(公告)日:2007-07-19
申请号:US10525867
申请日:2003-08-18
申请人: Heike Gielen-Haertwig , Volkhart Min-Jian Li , Ulrich Rosentreter , Karl-Heinz Schiemmer , Swen Allerheiligen , Leila Telan , Lars Bärfacker , Jörg Keldenich , Mary Fitzgerald , Kevin Nash , Barbara Albrecht , Dirk Meurer
发明人: Heike Gielen-Haertwig , Volkhart Min-Jian Li , Ulrich Rosentreter , Karl-Heinz Schiemmer , Swen Allerheiligen , Leila Telan , Lars Bärfacker , Jörg Keldenich , Mary Fitzgerald , Kevin Nash , Barbara Albrecht , Dirk Meurer
IPC分类号: A61K31/695 , C07F7/02 , A61K31/5377 , A61K31/496 , A61K31/4545 , C07D413/02 , C07D403/02 , C07D401/02
CPC分类号: C07D401/04 , C07D211/90 , C07D405/04 , C07D413/04 , C07D417/04
摘要: The invention relates to novel dihydropyridine derivatives, of Formula (I) processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
摘要翻译: 本发明涉及式(I)的新型二氢吡啶衍生物,其制备方法及其在药物中的用途,特别是用于治疗慢性阻塞性肺疾病,急性冠状动脉综合征,急性心肌梗塞和心力衰竭发展。