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公开(公告)号:US5246966A
公开(公告)日:1993-09-21
申请号:US816162
申请日:1991-12-30
申请人: Heinrich Meier , John E. B. Ransohoff , Trevor S. Abram , Peter Norman , Tudhope Stephen R. , Phillip J. Gardiner , Nigel J. Cuthbert , Hilary P. Francis
发明人: Heinrich Meier , John E. B. Ransohoff , Trevor S. Abram , Peter Norman , Tudhope Stephen R. , Phillip J. Gardiner , Nigel J. Cuthbert , Hilary P. Francis
IPC分类号: C07C323/62 , A61K31/19 , A61K31/194 , A61K31/235 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/12 , A61P29/00 , A61P37/08 , A61P43/00 , C07C20060101 , C07C69/734 , C07C319/20
CPC分类号: C07C69/734 , C07C323/62
摘要: The new substituted alkenoic acid derivatives can be prepared by reacting the appropriate aldehyde with a phosphonium compound. The compounds have leukotriene antagonistic properties and can be incorporated into pharmaceutical compositions.