-
公开(公告)号：US20240158338A1
公开(公告)日：2024-05-16
申请号：US18401076
申请日：2023-12-29
发明人： Ho Wan HAM , Hyun Cheol AN , Hee Joo KIM , Dong Jun KIM , Ja Eun ANN , Dong Yuel KWON , Sung Kyu LEE , Hwan Il JE , Bo Ra LEE , Yeong Rong PARK , Il Soo OH , Dae Woong LEE , Hyeon Jeong IM , Ill Hun CHO
IPC分类号： C07C233/63 , C07C237/26 , C07C257/16 , C07C323/62 , C07C327/46 , C07D401/12 , C07D407/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D519/00 , H10K50/858 , H10K59/80 , H10K85/60
CPC分类号： C07C233/63 , C07C237/26 , C07C257/16 , C07C323/62 , C07C327/46 , C07D401/12 , C07D407/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D519/00 , H10K50/858 , H10K59/879 , H10K85/615 , H10K85/653 , H10K85/654 , H10K85/655 , H10K85/656 , H10K85/6565
摘要： A novel compound for a capping layer, and an organic light-emitting device containing the same are disclosed.
-
公开(公告)号：US10017490B2
公开(公告)日：2018-07-10
申请号：US15267139
申请日：2016-09-15
发明人： Kiyoshi Kita , Akiyuki Suwa , Masatsugu Oda , Koji Tanaka
IPC分类号： A61K31/44 , A61K31/166 , A61K31/415 , C07D401/04 , C07D231/16 , C07D231/18 , C07D231/20 , C07D213/61 , C07D213/643 , C07C317/32 , C07C323/62 , C07C235/60 , C07C233/69 , C07C235/46 , C07C323/42 , C07D213/56 , C07D231/12 , C07D213/74
CPC分类号： C07D401/04 , A61K31/166 , A61K31/415 , A61K31/44 , C07C233/69 , C07C235/46 , C07C235/60 , C07C317/32 , C07C323/42 , C07C323/62 , C07D213/56 , C07D213/61 , C07D213/643 , C07D213/74 , C07D231/12 , C07D231/16 , C07D231/18 , C07D231/20
摘要： An object of the present invention is to provide a novel endoparasite control agent as a parasiticide, an antiprotozoal or the like. Provided is an endoparasite control agent comprising a carboxamide derivative represented by the general formula (I): or a salt thereof as an active ingredient.
-
公开(公告)号：US20180132482A1
公开(公告)日：2018-05-17
申请号：US15572107
申请日：2016-05-12
发明人： Takashi Furuya , Atsushi Okada , Hiroto Harayama , Yutaka Abe , Naoto Shimizu , Eiji Yasukouchi , Yutaka Kato
IPC分类号： A01N37/46 , A01N41/10 , A01N47/02 , C07C317/44 , C07C323/62
CPC分类号： A01N37/46 , A01N41/10 , A01N47/02 , C07C317/44 , C07C317/46 , C07C321/28 , C07C321/30 , C07C323/62
摘要： In crop production in the fields of agriculture, horticulture and the like, the damage caused by diseases etc. is still immense, and diseases resistant to existing microbicides have emerged. Under such circumstances, the development of novel agricultural and horticultural microbicides is desired.The present invention provides an anthranilic acid ester compound represented by the general formula (1): (wherein A1, A3 and A4 each represent a CH group, A2 represents a C-haloalkyl group, R1 represents an alkyl group, R3 represents a hydrogen atom or an acyl group, R4, R5 and R7 each represent a hydrogen atom, R6 represents a haloalkyl group, Z represents an alkyl group, and m represents 0, 1 or 2), or a salt thereof, an agricultural and horticultural microbicide comprising the compound or a salt thereof as an active ingredient, and a method for using the microbicide.
-
公开(公告)号：US09856239B1
公开(公告)日：2018-01-02
申请号：US15723785
申请日：2017-10-03
发明人： Yueheng Jiang
IPC分类号： C07D405/10 , C07D213/68 , C07D401/04 , C07D213/57 , C07D213/74 , C07D213/70 , C07B59/00 , C07C323/63
CPC分类号： C07D405/10 , A61K31/277 , A61K31/4418 , A61K31/4725 , C07B59/002 , C07B2200/05 , C07C319/20 , C07C323/62 , C07C323/63 , C07C2601/02 , C07D213/57 , C07D213/68 , C07D213/70 , C07D213/74 , C07D401/04
摘要： The present invention relates to the technical field of medicine, and specifically relates to the carboxylic acid compound represented by the chemical formula I or chemical formula II, and a pharmaceutically acceptable salt, a prodrug, and a solvate thereof, and a method for preparation thereof, as well as a pharmaceutical composition containing the described substances, and a use thereof.
-
5.发明授权公开(公告)号：US09822058B2
公开(公告)日：2017-11-21
申请号：US14390190
申请日：2013-03-13
发明人： Leticia M. Toledo-Sherman , Celia Dominguez , Michael Prime , William Leonard Mitchell , Peter Johnson , Naomi Went
IPC分类号： C07C62/38 , C07D307/94 , C07D309/10 , C07D215/18 , C07D311/58 , C07D317/46 , C07D317/60 , C07D319/18 , C07D233/64 , C07D235/26 , C07D403/10 , C07D405/08 , C07D405/10 , C07D405/12 , C07C317/44 , C07D413/08 , C07D413/10 , C07C323/62 , C07C229/22 , C07C229/46 , C07C229/48 , C07D257/04 , C07D203/08 , C07D263/58 , C07C235/82 , C07D207/08 , C07D271/07 , C07D207/337 , C07D295/155 , C07D305/06 , C07D305/08 , C07D307/54 , C07D307/80 , C07C69/757 , C07D203/10 , C07D307/79 , C07D413/12 , C07H15/20
CPC分类号： C07C62/38 , C07C69/757 , C07C229/22 , C07C229/46 , C07C229/48 , C07C235/82 , C07C317/44 , C07C323/62 , C07C2601/02 , C07C2602/50 , C07D203/08 , C07D203/10 , C07D207/08 , C07D207/337 , C07D215/18 , C07D233/64 , C07D235/26 , C07D257/04 , C07D263/58 , C07D271/07 , C07D295/155 , C07D305/06 , C07D305/08 , C07D307/54 , C07D307/79 , C07D307/80 , C07D307/94 , C07D309/10 , C07D311/58 , C07D317/46 , C07D317/60 , C07D319/18 , C07D403/10 , C07D405/08 , C07D405/10 , C07D405/12 , C07D413/08 , C07D413/10 , C07D413/12 , C07H15/20
摘要： Certain compounds, or pharmaceutically acceptable salts or prodrugs thereof, are provided herein. Also provided are pharmaceutical compositions comprising at least one compound, or pharmaceutically acceptable salt or prodrug thereof, described herein and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are described, which comprise administering to such patients an amount of at least one compound, or pharmaceutically acceptable salt or prodrug thereof, described herein effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include neurodegenerative disorders such as Huntington's disease. Also described are methods of treatment include administering at least one compound, or pharmaceutically acceptable salt or prodrug thereof, described herein as a single active agent or administering at least one compound, or pharmaceutically acceptable salt or prodrug thereof, described herein in combination with one or more other therapeutic agents. Also provided are methods for screening compounds capable of inhibiting KMO activity.
-
公开(公告)号：US09815782B2
公开(公告)日：2017-11-14
申请号：US15054243
申请日：2016-02-26
发明人： Mandar Deodhar , Alison Dorothy Findlay , Jonathan Stuart Foot , Wolfgang Jarolimek , Ian Alexander Mcdonald , Alan Duncan Robertson , Craig Ivan Turner
IPC分类号： A61K31/165 , C07C321/26 , C07C235/46 , C07C323/62 , C07C237/30 , C07C311/37 , C07C323/63 , C07C311/29 , C07C311/16
CPC分类号： C07C321/26 , C07C235/46 , C07C237/30 , C07C311/16 , C07C311/29 , C07C311/37 , C07C323/62 , C07C323/63
摘要： The present invention is related to the preparation and pharmaceutical use of substituted 3-haloallylamine derivatives as SSAO/VAP-1 inhibitors having the structure of Formula I, as defined in the specification: The invention also relates to methods of using compounds of Formula I, or pharmaceutically acceptable salt or derivatives thereof, for the treatment of a variety of indications, e.g., inflammatory diseases, ocular diseases, fibrotic diseases, diabetes-induced diseases and cancer.
-
公开(公告)号：US09790176B2
公开(公告)日：2017-10-17
申请号：US14420081
申请日：2013-08-05
IPC分类号： A61K31/275 , C07C255/00 , C07C323/62 , C07C317/44 , C07C255/29 , C07C255/62 , A61K31/277
CPC分类号： C07C323/62 , A61K31/277 , C07C255/29 , C07C255/62 , C07C317/44
摘要： The present invention relates to compounds for the treatment of mTOR (mammalian Target Of Rapamycin) pathway related diseases. Specifically, the present invention relates to the use of aminoactonitrile derivatives (AADs) in the treatment of mTOR pathway related diseases.
-
公开(公告)号：US09738595B2
公开(公告)日：2017-08-22
申请号：US14770557
申请日：2014-01-31
IPC分类号： C07C233/76 , C07D213/61 , A01N37/18 , A01N43/40 , C07D263/38 , C07C255/48 , C07C271/24 , C07C323/62 , C07C233/87 , C07C235/46 , A01C1/06 , A01N25/00 , A01N43/54 , C07D213/50 , C07D239/28
CPC分类号： C07C233/76 , A01C1/06 , A01N25/00 , A01N37/18 , A01N43/40 , A01N43/54 , C07C233/87 , C07C235/46 , C07C255/48 , C07C271/24 , C07C323/62 , C07C2601/02 , C07D213/50 , C07D213/61 , C07D239/28 , C07D263/38
摘要： Compounds of the formula (I), in which the substituents are as defined in claim 1, are suitable for use as nematicides.
-
9.发明申请公开(公告)号：US20170130029A1
公开(公告)日：2017-05-11
申请号：US15413676
申请日：2017-01-24
IPC分类号： C08K5/375 , C07C319/22 , C08K5/548 , C08K3/36 , C08L9/06 , C07C319/24 , C07C323/62
CPC分类号： C08K5/375 , B60C1/00 , C07C319/22 , C07C319/24 , C07C323/62 , C08K3/36 , C08K5/548 , C08L7/00 , C08L9/00 , C08L9/06 , C08L2205/025 , C08L2205/03 , C08L21/00
摘要： The present invention relates to polysulfides of the formula (I) where the cations K1+ and K2+ are each independently any monovalent cation or the fraction of any polyvalent cation which corresponds to a positive charge of one, and n is 2, 3, 4, 5, 6, these having a low residual acidity, and to processes for producing these polysulfide mixtures, to the use of the polysulfides of the formula (I) in rubber mixtures, to the corresponding rubber mixtures, to rubber vulcanizates produced therefrom and to the use thereof.
-
10.发明申请公开(公告)号：US20160244406A1
公开(公告)日：2016-08-25
申请号：US15054243
申请日：2016-02-26
发明人： Mandar Deodhar , Alison Dorothy Findlay , Jonathan Stuart Foot , Wolfgang Jarolimek , Ian Alexander Mcdonald , Alan Duncan Robertson , Craig Ivan Turner
IPC分类号： C07C321/26 , C07C311/16 , C07C237/30
CPC分类号： C07C321/26 , C07C235/46 , C07C237/30 , C07C311/16 , C07C311/29 , C07C311/37 , C07C323/62 , C07C323/63
摘要： The present invention is related to the preparation and pharmaceutical use of substituted 3-haloallylamine derivatives as SSAO/VAP-1 inhibitors having the structure of Formula I, as defined in the specification: The invention also relates to methods of using compounds of Formula I, or pharmaceutically acceptable salt or derivatives thereof, for the treatment of a variety of indications, e.g., inflammatory diseases, ocular diseases, fibrotic diseases, diabetes-induced diseases and cancer.
摘要翻译： 本发明涉及取代的3-卤代烯丙胺衍生物的制备和药物用途，如具有式I结构的SSAO / VAP-1抑制剂，如说明书中所定义：本发明还涉及使用式I化合物， 或其药学上可接受的盐或衍生物，用于治疗各种适应症，例如炎症性疾病，眼部疾病，纤维化疾病，糖尿病诱发的疾病和癌症。
-
-
-
-
-
-
-
-
-
搜索结果
1056 条记录 (耗时 0.054 秒)
