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公开(公告)号:US08158660B2
公开(公告)日:2012-04-17
申请号:US12437704
申请日:2009-05-08
申请人: Hengmiao Cheng , Xiao Hu , Kevin D. Jerome , Mark G. Obukowicz , Lisa Maria Olson , Paul V. Rucker , Ronald Keith Webber
发明人: Hengmiao Cheng , Xiao Hu , Kevin D. Jerome , Mark G. Obukowicz , Lisa Maria Olson , Paul V. Rucker , Ronald Keith Webber
IPC分类号: A61K31/44
CPC分类号: C07D213/89 , A61K31/44 , C07D213/72 , C07F9/58 , Y10S514/886
摘要: The present invention is directed to compounds of Formula I: or salt thereof, which are modulators of the glucocorticoid receptor. The compounds and salts of the invention are useful in the treatment of conditions mediated by glucocorticoid receptor activity.
摘要翻译: 本发明涉及式I化合物或其盐,它们是糖皮质激素受体的调节剂。 本发明的化合物和盐可用于治疗由糖皮质激素受体活性介导的病症。
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公开(公告)号:US08445520B2
公开(公告)日:2013-05-21
申请号:US13333104
申请日:2011-12-21
申请人: Hengmiao Cheng , Xiao Hu , Kevin D. Jerome , Mark G. Obukowicz , Lisa Maria Olson , Paul V. Rucker , Ronald Keith Webber
发明人: Hengmiao Cheng , Xiao Hu , Kevin D. Jerome , Mark G. Obukowicz , Lisa Maria Olson , Paul V. Rucker , Ronald Keith Webber
IPC分类号: A61K31/44 , C07D211/68 , C12N5/00
CPC分类号: C07D213/89 , A61K31/44 , C07D213/72 , C07F9/58 , Y10S514/886
摘要: The present invention is directed to compounds of Formula I: or salt thereof, which are modulators of the glucocorticoid receptor. The compounds and salts of the invention are useful in the treatment of conditions mediated by glucocorticoid receptor activity.
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