-
1.
公开(公告)号:US20130331383A1
公开(公告)日:2013-12-12
申请号:US13897168
申请日:2013-05-17
申请人: Henna Swamy , Laurent Brard , Rakesh K. Singh , Satyan Kalkunte , Narasimha Swamy , Giselle L. Saulnier Sholler , Kyu Kwang Kim
发明人: Giselle L. Saulnier Sholler , Narasimha SWAMY , Satyan KALKUNTE , Rakesh K. SINGH , Laurent BRARD , Kyu Kwang KIM
IPC分类号: A61K31/541 , A61K45/06
CPC分类号: A61K31/541 , A61K31/34 , A61K31/345 , A61K45/06
摘要: The invention is directed to the synthesis and use of nitrofuran compounds, especially Nifurtimox, as medicaments to treat cancer, especially neuroblastoma, and to inhibit angiogenesis. The invention also provides compositions, unit dosage forms, and kits comprising the compounds.
摘要翻译: 本发明涉及硝基呋喃化合物,特别是Nifurtimox的合成和用途,作为治疗癌症,特别是神经母细胞瘤的药物,并且用于抑制血管生成。 本发明还提供组合物,单位剂量形式和包含该化合物的试剂盒。