专利检索 ap:("Herve Grouiller" OR "Fabien Christ") AND inv:"Fabien Christ" 第 1 页

1.

发明授权
Inert matrix based on polycaprolactone for the oral administration of a drug, and method for the preparation of the galenic form comprising this matrix 失效
标题翻译：用于口服给药的基于聚己内酯的惰性基质，以及制备包含该基质的盖仑型的方法

公开(公告)号：US4629624A

公开(公告)日：1986-12-16

申请号：US686214

申请日：1984-12-26

申请人： Herve Grouiller , Fabien Christ

发明人： Herve Grouiller , Fabien Christ

IPC分类号： A61K9/20 , A61K9/22 , A61K9/26 , A61K47/34 , A61K31/74

CPC分类号： A61K9/204 , Y10S514/951

摘要： The present invention relates to a new inert matrix having adjustable porosity and hardness.This matrix comprises polycaprolactone having an average molecular weight of between 2000 and 70,000, which is in the form of agglomerated grains having an average diameter of between 50 and 500 .mu.m and has a degree of crystallinity of at least 75%. The invention relates to the method for the preparation of a porous galenic form by means of the said matrix.

摘要翻译： 本发明涉及一种具有可调孔性和硬度的新的惰性基体。该基质包含平均分子量为2000〜70,000的聚己内酯，其为平均直径为50〜500μm，结晶度为75％以上的凝聚颗粒的形式。本发明涉及通过所述基质制备多孔盖仑形式的方法。