公开(公告)号：US20060235045A1

公开(公告)日：2006-10-19

申请号：US10565828

申请日：2004-07-27

申请人： Hidetsugu Takagaki ,  Yasuo Aoki ,  Mitsuteru Ishiwara ,  Nobuaki Mizutani

发明人： Hidetsugu Takagaki ,  Yasuo Aoki ,  Mitsuteru Ishiwara ,  Nobuaki Mizutani

IPC分类号： A61K31/4704

CPC分类号： A61K31/4704 ,  C07D215/38

摘要： This therapeutic agent for chronic obstructive pulmonary disease comprises, an active ingredient, at least one of a 7-aminoquinolinone derivative represented by the general formula (I): wherein R1 represents a hydrogen atom or an alkyl group; R2 and R3 each represents a group selected from a hydrogen atom, an acyl group, an alkyl group and an alkenyl group; and R4 and R5 each represents a group selected from a hydrogen atom, an acyl group, an alkyl group, an alkenyl group and an aralkyl group, and its physiologically acceptable salt.

摘要翻译： 用于慢性阻塞性肺疾病的治疗剂包含活性成分，由通式（I）表示的7-氨基喹啉酮衍生物中的至少一种：其中R 1表示氢原子或烷基 ; R 2和R 3各自表示选自氢原子，酰基，烷基和烯基的基团; R 4和R 5各自表示选自氢原子，酰基，烷基，烯基和芳烷基的基团，其生理上可接受的 盐。

公开(公告)号：US08980914B2

公开(公告)日：2015-03-17

申请号：US10565828

申请日：2004-07-27

申请人： Hidetsugu Takagaki ,  Yasuo Aoki ,  Mitsuteru Ishiwara ,  Nobuaki Mizutani

发明人： Hidetsugu Takagaki ,  Yasuo Aoki ,  Mitsuteru Ishiwara ,  Nobuaki Mizutani

IPC分类号： A61K31/00 ,  A61K31/4704 ,  C07D215/38

CPC分类号： A61K31/4704 ,  C07D215/38

摘要： This therapeutic agent for chronic obstructive pulmonary disease comprises, an active ingredient, at least one of a 7-aminoquinolinone derivative represented by the general formula (I): wherein R1 represents a hydrogen atom or an alkyl group; R2 and R3 each represents a group selected from a hydrogen atom, an acyl group, an alkyl group and an alkenyl group; and R4 and R5 each represents a group selected from a hydrogen atom, an acyl group, an alkyl group, an alkenyl group and an aralkyl group, and its physiologically acceptable salt.

摘要翻译： 该慢性阻塞性肺疾病治疗剂包含活性成分，由通式（I）表示的7-氨基喹啉酮衍生物中的至少一种：其中R1表示氢原子或烷基; R2和R3各自表示选自氢原子，酰基，烷基和烯基的基团; R 4和R 5各自表示选自氢原子，酰基，烷基，烯基和芳烷基的基团及其生理学上可接受的盐。

公开(公告)号：US20110021621A1

公开(公告)日：2011-01-27

申请号：US12923589

申请日：2010-09-29

申请人： Hidetsugu Takagaki ,  Yasuo Aoki ,  Mitsuteru Ishiwara

发明人： Hidetsugu Takagaki ,  Yasuo Aoki ,  Mitsuteru Ishiwara

IPC分类号： A61K31/353 ,  C07D311/56 ,  A61P7/00 ,  A61P9/00

CPC分类号： C07D311/56 ,  A61K31/37

摘要： The present invention relate to a drug for treating circulatory insufficiency containing a benzopyran derivative represented by the following general formula (I): and/or a physiologically acceptable salt thereof as an active ingredient, wherein R1 is an alkyl group having 1 to 10 carbon atoms, or an alkenyl group having 2 to 10 carbon atoms; and any one of R2, R3, R4 and R5 is a hydroxyl group, an alkoxy group, an alkenyloxy group, an alkoxy group substituted with a hydroxyl group, or an alkoxy group substituted with a carboxy group, and the others are hydrogen atoms.

摘要翻译： 本发明涉及含有下列通式（I）表示的苯并吡喃衍生物的循环功能不全药物：和/或其生理学上可接受的盐作为有效成分，其中R1为碳原子数1〜10的烷基 ，或具有2〜10个碳原子的烯基; R 2，R 3，R 4和R 5中的任一个是羟基，烷氧基，烯氧基，被羟基取代的烷氧基或被羧基取代的烷氧基，其它是氢原子。

公开(公告)号：US20090099256A1

公开(公告)日：2009-04-16

申请号：US12084052

申请日：2006-10-23

申请人： Hidetsugu Takagaki ,  Yasuo Aoki ,  Mitsuteru Ishiwara

发明人： Hidetsugu Takagaki ,  Yasuo Aoki ,  Mitsuteru Ishiwara

IPC分类号： A61K31/353 ,  C07D311/56 ,  A61P9/00

CPC分类号： C07D311/56 ,  A61K31/37

摘要： The present invention relate to a drug for treating circulatory insufficiency containing a benzopyran derivative represented by the following general formula (I): and/or a physiologically acceptable salt thereof as an active ingredient, wherein R1 is an alkyl group having 1 to 10 carbon atoms, or an alkenyl group having 2 to 10 carbon atoms; and any one of R2, R3, R4 and R5 is a hydroxyl group, an alkoxy group, an alkenyloxy group, an alkoxy group substituted with a hydroxyl group, or an alkoxy group substituted with a carboxy group, and the others are hydrogen atoms.

摘要翻译： 本发明涉及含有下列通式（I）表示的苯并吡喃衍生物的循环功能不全药物：和/或其生理学上可接受的盐作为有效成分，其中R1为碳原子数1〜10的烷基 ，或具有2〜10个碳原子的烯基; R 2，R 3，R 4和R 5中的任一个是羟基，烷氧基，烯氧基，被羟基取代的烷氧基或被羧基取代的烷氧基，其它是氢原子。