公开(公告)号：US20090148426A1

公开(公告)日：2009-06-11

申请号：US12067783

申请日：2006-09-21

申请人： Hideyuki Kishida ,  Taizuo Kawabe ,  Kazunori Hosoe

发明人： Hideyuki Kishida ,  Taizuo Kawabe ,  Kazunori Hosoe

IPC分类号： A61K38/43 ,  C07C43/205 ,  A61K31/09 ,  A61K31/122

CPC分类号： A61K31/05 ,  A61K31/122

摘要： The present invention relates to a composition for life extension, comprising reduced coenzyme Q10 as an active ingredient, as well as relates to a method of extending a life span using the composition comprising reduced coenzyme Q10 as an active ingredient. In the present invention, it has been found that long-term ingestion of feed that contains reduced coenzyme Q10 enables the life span of senescence-accelerated model mice to be extended. No sign indicating toxicity is observed in the senescence-accelerated model mice that have been fed with reduced coenzyme Q10 over a long period. Based on these findings, it was found that the composition containing reduce coenzyme Q10 as an active ingredient has potential to be a composition for life extension with high safety, capable of being taken for a long period. The present invention provides a composition, which can extend the life span of humans or animals, enables them to spend active and healthy senectitudes and shows high safety during the ingestion over a long period.

摘要翻译： 本发明涉及一种延长寿命的组合物，其包含还原型辅酶Q10作为活性成分，以及涉及使用包含还原型辅酶Q10作为活性成分的组合物延长使用寿命的方法。 在本发明中，已经发现，含有还原型辅酶Q10的饲料的长期摄入使得能够延长衰老加速模型小鼠的寿命。 没有迹象表明，在衰老加速模型小鼠中观察到毒性，这些老鼠在长时间内补充还原型辅酶Q10。 基于这些发现，发现含有还原型辅酶Q10作为活性成分的组合物具有潜在的延长寿命的组合物，其安全性高，能够长时间服用。 本发明提供一种能够延长人类或动物寿命的组合物，使其能够在长时间摄取过程中花费积极和健康的感觉并显示高安全性。