公开(公告)号：US20070082024A1

公开(公告)日：2007-04-12

申请号：US10577135

申请日：2004-10-20

申请人： Hitoshi Matsumoto ,  Yuko Nakamura ,  Megumi Yamagishi ,  Kyoto Ito

发明人： Hitoshi Matsumoto ,  Yuko Nakamura ,  Megumi Yamagishi ,  Kyoto Ito

IPC分类号： A61K31/7048 ,  A61K31/353 ,  A61K8/73

CPC分类号： C07H17/065 ,  A23L33/105 ,  A61K8/97 ,  A61K31/7048 ,  A61K2800/782 ,  A61Q19/02

摘要： A tyrosinase activity inhibitor and an ameliorant for facial blood flow that are excellent in terms of safety, and medicinal compositions, food compositions, and cosmetic preparations that contain the inhibitor and the ameliorant as active ingredients are provided. A tyrosinase activity inhibitor and an ameliorant for facial blood flow that contain anthocyan obtained by concentration or extraction of plant material, and medicinal compositions, food compositions, and cosmetic preparations that have an inhibitory action on tyrosinase activity and ameliorating action on facial blood flow are provided.

摘要翻译： 提供了一种酪氨酸酶活性抑制剂和安全性优异的面部血流量改善剂，以及含有抑制剂和改善剂作为活性成分的药物组合物，食品组合物和化妆品制剂。 提供了含有通过浓缩或提取植物材料获得的花青的面部血液流出物的酪氨酸酶活性抑制剂和改善剂，以及对酪氨酸酶活性具有抑制作用并改善对面部血流的作用的药物组合物，食品组合物和化妆品制剂。 。

公开(公告)号：US07863248B2

公开(公告)日：2011-01-04

申请号：US10577135

申请日：2004-10-20

申请人： Hitoshi Matsumoto ,  Yuko Nakamura ,  Megumi Yamagishi ,  Kyoko Ito

发明人： Hitoshi Matsumoto ,  Yuko Nakamura ,  Megumi Yamagishi ,  Kyoko Ito

IPC分类号： A61K31/70

CPC分类号： C07H17/065 ,  A23L33/105 ,  A61K8/97 ,  A61K31/7048 ,  A61K2800/782 ,  A61Q19/02

摘要： A tyrosinase activity inhibitor and an ameliorant for facial blood flow that are excellent in terms of safety, and medicinal compositions, food compositions, and cosmetic preparations that contain the inhibitor and the ameliorant as active ingredients are provided. A tyrosinase activity inhibitor and an ameliorant for facial blood flow that contain anthocyan obtained by concentration or extraction of plant material, and medicinal compositions, food compositions, and cosmetic preparations that have an inhibitory action on tyrosinase activity and ameliorating action on facial blood flow are provided.

摘要翻译： 提供了一种酪氨酸酶活性抑制剂和安全性优异的面部血流量改善剂，以及含有抑制剂和改善剂作为活性成分的药物组合物，食品组合物和化妆品制剂。 提供了含有通过浓缩或提取植物材料获得的花青的面部血液流出物的酪氨酸酶活性抑制剂和改善剂，以及对酪氨酸酶活性具有抑制作用并改善对面部血流的作用的药物组合物，食品组合物和化妆品制剂。 。

公开(公告)号：US20070060533A1

公开(公告)日：2007-03-15

申请号：US10576350

申请日：2004-10-19

申请人： Masayuki Yoshikawa ,  Hisashi Matsuda ,  Megumi Yamagishi ,  Hitoshi Matsumoto

发明人： Masayuki Yoshikawa ,  Hisashi Matsuda ,  Megumi Yamagishi ,  Hitoshi Matsumoto

IPC分类号： A61K36/185 ,  A61K31/7048 ,  A61K31/353

CPC分类号： A61K31/7048 ,  A23L2/52 ,  A23L33/105 ,  A23V2002/00 ,  A61K36/185 ,  A23V2250/2104

摘要： Provided are: an inhibitor of the formation of an advanced glycation end product (AGE) and aldose reductase for treating and preventing both various diseases relating to AGE formation, such as complications related to diabetes and various diseases relating to aldose reductase inhibition; pharmaceutical preparations, compositions, and food and drink that contain these active ingredients; and pharmaceutical preparations and foods prepared by blending compositions containing anthocyanin, because such anthocyanin obtained through condensation or extraction from raw plant materials or the like is useful as an inhibitor of AGE formation and aldose reductase.

摘要翻译： 提供：形成晚期糖基化终产物（AGE）和醛糖还原酶的抑制剂，用于治疗和预防与AGE形成相关的各种疾病，例如与糖尿病有关的并发症和与醛糖还原酶抑制有关的各种疾病; 药物制剂，组合物和含有这些活性成分的食物和饮料; 以及通过配合含有花青素的组合物配制的药物制剂和食品，因为通过从植物原料等冷凝或提取得到的花青素可用作AGE形成抑制剂和醛糖还原酶。