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公开(公告)号：US10233184B2
公开(公告)日：2019-03-19
申请号：US15689136
申请日：2017-08-29
Applicant: Hoffmann-La Roche Inc.
Inventor： Lu Gao , Chungen Liang , Hongying Yun , Xiufang Zheng , Jianping Wang , Kun Miao , Bo Zhang
IPC: C07D473/24 , A61K31/522
Abstract: The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
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公开(公告)号：US11242345B2
公开(公告)日：2022-02-08
申请号：US16530229
申请日：2019-08-02
Applicant: Hoffmann-La Roche Inc.
Inventor： Chungen Liang , Jianping Wang , Kun Miao , Hongying Yun , Xiufang Zheng
IPC: C07D473/24
Abstract: The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
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公开(公告)号：US11220502B2
公开(公告)日：2022-01-11
申请号：US16990858
申请日：2020-08-11
Applicant: Hoffmann-La Roche Inc.
Inventor： Chungen Liang , Jianping Wang , Hongying Yun , Kun Miao
IPC: C07D473/24
Abstract: The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salts, enantiomers or diastereomers thereof, and compositions including the compounds and methods of using the compounds.
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公开(公告)号：US10752630B2
公开(公告)日：2020-08-25
申请号：US16260744
申请日：2019-01-29
Applicant: Hoffmann-La Roche Inc.
Inventor： Lu Gao , Chungen Liang , Hongying Yun , Xiufang Zheng , Jianping Wang , Kun Miao , Bo Zhang
IPC: A61P43/00 , A61P37/04 , A61P31/20 , A61P31/00 , A61K31/522 , C07D473/24
Abstract: The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
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公开(公告)号：US20220064128A1
公开(公告)日：2022-03-03
申请号：US17445989
申请日：2021-08-26
Applicant: Hoffmann-La Roche Inc.
Inventor： Chungen Liang , Hongying Yun , Weixing Zhang , Kun Miao , Jianguo Chen , Yao Wu
IPC: C07D241/24 , C07C243/34 , C07D207/26 , C07D211/76 , C07D231/12 , C07D233/64 , C07D209/42 , C07D261/18 , C07D403/12 , C07D235/24 , C07D401/04 , C07D413/12 , C07C311/35
Abstract: The present invention relates to compounds of formula (I), wherein R1-R5 and L are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.
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Patent Agency Ranking
6.发明申请公开(公告)号：US20170275286A1
公开(公告)日：2017-09-28
申请号：US15621080
申请日：2017-06-13
Applicant: Hoffmann-La Roche Inc.
Inventor： Chungen Liang , Jianping Wang , Kun Miao , Hongying Yun , Xiufang Zheng
IPC: C07D473/24
CPC classification number: C07D473/24
Abstract: The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
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7.发明授权公开(公告)号：US09708325B2
公开(公告)日：2017-07-18
申请号：US15148309
申请日：2016-05-06
Applicant: Hoffmann-La Roche Inc.
Inventor： Chungen Liang , Jianping Wang , Kun Miao , Hongying Yun , Xiufang Zheng
IPC: A61K31/522 , C07D473/24
CPC classification number: C07D473/24
Abstract: The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
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8.发明申请Novel Sulfonimidoylpurinone Compounds and Derivatives for the Treatment and Prophylaxis of Virus Infection 有权用于治疗和预防病毒感染的新型磺酰亚胺基呋喃酮化合物和衍生物公开(公告)号：US20160326177A1
公开(公告)日：2016-11-10
申请号：US15148309
申请日：2016-05-06
Applicant: Hoffmann-La Roche Inc.
Inventor： Chungen Liang , Jianping Wang , Kun Miao , Hongying Yun , Xiufang Zheng
IPC: C07D473/24
CPC classification number: C07D473/24
Abstract: The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
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公开(公告)号：US12060333B2
公开(公告)日：2024-08-13
申请号：US17445989
申请日：2021-08-26
Applicant: Hoffmann-La Roche Inc.
Inventor： Chungen Liang , Hongying Yun , Weixing Zhang , Kun Miao , Jianguo Chen , Yao Wu
IPC: C07D241/24 , C07C243/34 , C07C311/35 , C07D207/26 , C07D209/42 , C07D211/76 , C07D231/12 , C07D233/64 , C07D235/24 , C07D261/18 , C07D401/04 , C07D403/12 , C07D413/12
CPC classification number: C07D241/24 , C07C243/34 , C07C311/35 , C07D207/26 , C07D209/42 , C07D211/76 , C07D231/12 , C07D233/64 , C07D235/24 , C07D261/18 , C07D401/04 , C07D403/12 , C07D413/12
Abstract: The present invention relates to compounds of formula (I),
wherein R1-R5 and L are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.-
公开(公告)号：US10399983B2
公开(公告)日：2019-09-03
申请号：US15621080
申请日：2017-06-13
Applicant: Hoffmann-La Roche Inc.
Inventor： Chungen Liang , Jianping Wang , Kun Miao , Hongying Yun , Xiufang Zheng
IPC: C07D473/24
Abstract: The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
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