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公开(公告)号：US20220363665A1
公开(公告)日：2022-11-17
申请号：US17641894
申请日：2020-09-09
发明人： Fabian DEY , Haixia LIU , Hong SHEN , Weixing ZHANG , Zhiwei ZHANG , Wei ZHU
IPC分类号： C07D401/10 , C07D401/12 , C07D215/38 , C07D498/08 , C07D471/08 , C07D487/10 , A61P37/06
摘要： The present invention relates to compounds of formula (I), (I), wherein R1, R2 and R3 are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
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公开(公告)号：US20210395239A1
公开(公告)日：2021-12-23
申请号：US17278416
申请日：2019-09-25
发明人： Fabian DEY , Jianguo CHEN , Haixia LIU , Yafei LIU , Hong SHEN , Weixing ZHANG , Zhiwei ZHANG , Wei ZHU
IPC分类号： C07D413/14 , C07D498/08 , C07D498/10 , C07D471/04
摘要： The present invention relates to compounds of formula (I), wherein R1 to R3, A and Q are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
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公开(公告)号：US20220112187A1
公开(公告)日：2022-04-14
申请号：US17275498
申请日：2018-09-11
发明人： Haixia LIU , Hong SHEN , Wei ZHU , Taishan HU , Zhiwei ZHANG , Fabian DEY
IPC分类号： C07D471/04 , C07D519/00 , A61P37/06
摘要： The present invention relates to compounds of formula (I), wherein R1, R2, R3, R4 and X are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
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公开(公告)号：US20210309658A1
公开(公告)日：2021-10-07
申请号：US17331599
申请日：2021-05-26
发明人： Fabian DEY , Yimin HU , Yongqiang LIU , Hong SHEN , Houguang SHI , Xuefei TAN , Shixiang YAN , Weixing ZHANG , Zhiwei ZHANG , Chengang ZHOU , Mingwei ZHOU , Wei ZHU
IPC分类号： C07D471/04 , A61P31/04 , C07D519/00
摘要： The present invention relates to novel compounds of formula (I), wherein R1, R2, R3, R4, R5 and R6 are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
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公开(公告)号：US20210309657A1
公开(公告)日：2021-10-07
申请号：US17331598
申请日：2021-05-26
发明人： Fabian DEY , Yimin HU , Yongqiang LIU , Hong SHEN , Houguang SHI , Xuefei TAN , Shixiang YAN , Weixing ZHANG , Zhiwei ZHANG , Chengang ZHOU , Mingwei ZHOU , Wei ZHU
IPC分类号： C07D471/04 , C07D519/00 , A61P31/04
摘要： The present invention relates to novel compounds of formula (I), wherein R1, R2, R3, R4, R5 and R6 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
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![HEXAHYDRO-1H-PYRAZINO[1,2-A]PYRAZINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE](/abs-image/US/2022/10/27/US20220340597A1/abs.jpg.150x150.jpg)
公开(公告)号：US20220340597A1
公开(公告)日：2022-10-27
申请号：US17602057
申请日：2020-04-07
发明人： Wei ZHU , Zhiwei ZHANG , Zhisen ZHANG , Hong SHEN , Yongfu LIU , Yafei LIU , Haixia LIU , Buyu KOU , Fabian DEY , Lue DAI , Linuo ZHU
IPC分类号： C07D519/00 , C07D487/04 , A61P37/06
摘要： The present invention relates to compounds of formula (I), wherein R1 to R3, n and A are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.
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