公开(公告)号：US09320445B2

公开(公告)日：2016-04-26

申请号：US13215311

申请日：2011-08-23

申请人： Hongxuan Zhang

发明人： Hongxuan Zhang

IPC分类号： A61B5/02 ,  A61B5/021 ,  A61B5/00 ,  G06F19/00

CPC分类号： A61B5/021 ,  A61B5/7264 ,  G16H50/20

摘要： A system provides cardiac arrhythmia detection and performs blood pressure analysis of multiple catheter channels of blood pressure signals to characterize heart hemodynamic activity. A system for heart performance characterization and abnormality detection includes a repository, data processor and output processor. The repository of data comprises, first distribution data representing a probability distribution of a first patient parameter over a first time period and acquired on a first occasion and second distribution data representing a probability distribution of the first patient parameter over a second time period and acquired on a second occasion subsequent to the first occasion. The data processor calculates an overlap indicator indicating degree of overlap of the first distribution data and the second distribution data in a predetermined interval of the distributions. The output processor provides the calculated overlap indicator to a destination device.

摘要翻译： 系统提供心律失常检测，并对血压信号的多个导管通道进行血压分析，以表征心脏血流动力学活动。 用于心脏性能表征和异常检测的系统包括储存库，数据处理器和输出处理器。 数据存储库包括：第一分发数据，表示在第一时间段内第一个患者参数的概率分布并在第一时间获取，第二分布数据表示在第二时间段内第一个患者参数的概率分布， 第二次在第一次之后。 数据处理器在分布的预定间隔中计算指示第一分发数据和第二分发数据的重叠程度的重叠指示符。 输出处理器将计算出的重叠指示符提供给目标设备。

公开(公告)号：US09050016B2

公开(公告)日：2015-06-09

申请号：US12702805

申请日：2010-02-09

申请人： Hongxuan Zhang

发明人： Hongxuan Zhang

IPC分类号： A61B5/05 ,  A61B5/053 ,  A61B5/0452 ,  A61B5/00

CPC分类号： A61B5/053 ,  A61B5/0452 ,  A61B5/7217

摘要： A system for heart performance characterization receives an electrical signal indicating heart electrical activity of a patient over a heart beat cycle. The electrical signal is acquired at a particular anatomical location. A gating signal generator generates a gating signal for use in identifying a particular portion of the heart beat cycle. An acquisition device, responsive to the gating signal, derives first and second voltage potentials from the received electrical signal. The first voltage potential comprises a voltage potential derived over a time period comprising a heart beat cycle and the second voltage potential comprises a voltage potential derived over a time period comprising a particular portion of the heart beat cycle. A computation processor derives a dynamic impedance representative value by adjusting a baseline impedance value by a ratio of the first and second voltage potentials. The dynamic impedance represents an average impedance at the particular anatomical location over a time period comprising the particular portion of the heart beat cycle.

摘要翻译： 用于心脏性能表征的系统接收指示心跳周期的患者的心脏电活动的电信号。 在特定解剖位置获取电信号。 选通信号发生器产生用于识别心跳周期的特定部分的门控信号。 响应于门控信号的采集装置从接收的电信号中导出第一和第二电压电位。 第一电压电位包括在包括心跳周期的时间段内导出的电压电位，并且第二电压电势包括在包括心跳周期的特定部分的时间段内导出的电压电位。 计算处理器通过以第一和第二电压电位的比率调整基线阻抗值来得出动态阻抗代表值。 动态阻抗表示在包括心跳周期的特定部分的时间段内的特定解剖学位置处的平均阻抗。

公开(公告)号：US08862216B2

公开(公告)日：2014-10-14

申请号：US13760124

申请日：2013-02-06

申请人： Hongxuan Zhang

发明人： Hongxuan Zhang

IPC分类号： A61B5/0452 ,  G06F3/0481 ,  A61B5/00 ,  A61B5/0402

CPC分类号： A61B5/0402 ,  A61B5/0452 ,  A61B5/7203 ,  A61B5/725 ,  G06F3/0481

摘要： A system for adaptively processing patient monitoring signals comprises an input processor for acquiring a signal having amplitude representing electrical activity of a patient heart over time. A signal processor identifies different portions of the signal associated with different phases of cardiac activity by, inverting the signal to provide an inverted signal, aligning the signal and the inverted signal in amplitude during a cardiac rest portion and identifying one or more of the different portions in response to an intersection point of the signal and the inverted signal. Multiple adaptive signal filters are used to filter multiple bandwidths of corresponding different portions of the signal.

摘要翻译： 用于自适应地处理患者监测信号的系统包括用于获取具有表示患者心脏随时间的电活动的幅度的信号的输入处理器。 信号处理器通过以下方式识别与心脏活动的不同相位相关联的信号的不同部分：反相信号以提供反相信号，在心脏休息部分期间以幅度对准信号和反相信号，并且识别一个或多个不同部分 响应于信号和反相信号的交点。 多个自适应信号滤波器用于滤除信号的相应不同部分的多个带宽。

公开(公告)号：US08666483B2

公开(公告)日：2014-03-04

申请号：US12250141

申请日：2008-10-13

申请人： Hongxuan Zhang

发明人： Hongxuan Zhang

IPC分类号： A61B5/00

CPC分类号： A61B5/046 ,  A61B5/04017 ,  A61B5/7203 ,  A61B5/7242

摘要： A system and method provides monitoring for atrial fibrillation. A data acquisition processor acquires a cardiac signal data stream from a patient and a wave detector detects an R-wave in a cardiac signal of the data stream. A T-wave in the cardiac signal occurring after the detected R-wave and a Q-wave in a subsequent cardiac signal of the data stream is also detected by the wave detector. A filter provides signal gating and extraction of data representing a Region of Interest (ROI) time window from the detected T-wave to the Q-wave. An integration processor detects characteristics of a P wave signal occurring within the ROI time window. At least one of the detected P wave characteristics is compared to characteristics derived from data representing at least one P wave signal and generating an output signal in response to the comparison for use in determining if the patient is in atrial fibrillation.

摘要翻译： 系统和方法提供心房颤动监测。 数据采集​​处理器从患者获取心脏信号数据流，并且波检测器检测数据流的心脏信号中的R波。 在检测到的R波之后发生的心脏信号中的T波和数据流的后续心脏信号中的Q波也被波检测器检测到。 滤波器提供从检测到的T波到Q波的表示感兴趣区域（ROI）时间窗口的数据的信号门控和提取。 集成处理器检测在ROI时间窗内发生的P波信号的特性。 将检测到的P波特性中的至少一个与从表示至少一个P波信号的数据导出的特性进行比较，并响应于用于确定患者是否处于心房颤动的比较而产生输出信号。

公开(公告)号：US20130345573A1

公开(公告)日：2013-12-26

申请号：US13923717

申请日：2013-06-21

申请人： Soroosh Kargar ,  Steve D. Quam ,  Hongxuan Zhang

发明人： Soroosh Kargar ,  Steve D. Quam ,  Hongxuan Zhang

IPC分类号： A61B5/021

CPC分类号： A61B5/021 ,  A61B5/107

摘要： Disclosed herein is a framework for facilitating adaptive control of monitoring devices. In accordance with one aspect, a position detector detects a chest elevation level and provides chest elevation level data. A processor uses the chest elevation level data to determine a heart elevation level with respect to a reference level. A comparator compares the determined heart elevation level with an elevation level of a monitoring device with respect to the reference level. In response to the comparison, a movement system adjusts the elevation level of the monitoring device.

摘要翻译： 这里公开了一种用于促进监控设备的自适应控制的框架。 根据一个方面，位置检测器检测胸部仰卧位并提供胸部仰卧位数据。 处理器使用胸部仰卧位数据来确定相对于参考水平的心脏仰角水平。 比较器将确定的心脏高程水平与监测装置相对于参考水平的高程水平进行比较。 响应于比较，运动系统调节监视装置的高程。

公开(公告)号：US20130245478A1

公开(公告)日：2013-09-19

申请号：US13760124

申请日：2013-02-06

申请人： Hongxuan Zhang

发明人： Hongxuan Zhang

IPC分类号： A61B5/0402 ,  G06F3/0481 ,  A61B5/0452

CPC分类号： A61B5/0402 ,  A61B5/0452 ,  A61B5/7203 ,  A61B5/725 ,  G06F3/0481

摘要： A system for adaptively processing patient monitoring signals comprises an input processor for acquiring a signal having amplitude representing electrical activity of a patient heart over time. A signal processor identifies different portions of the signal associated with different phases of cardiac activity by, inverting the signal to provide an inverted signal, aligning the signal and the inverted signal in amplitude during a cardiac rest portion and identifying one or more of the different portions in response to an intersection point of the signal and the inverted signal. Multiple adaptive signal filters are used to filter multiple bandwidths of corresponding different portions of the signal.

摘要翻译： 用于自适应地处理患者监测信号的系统包括用于获取具有表示患者心脏随时间的电活动的幅度的信号的输入处理器。 信号处理器通过以下方式识别与心脏活动的不同相位相关联的信号的不同部分：反相信号以提供反相信号，在心脏休息部分期间以幅度对准信号和反相信号，并且识别一个或多个不同部分 响应于信号和反相信号的交点。 多个自适应信号滤波器用于滤除信号的相应不同部分的多个带宽。

公开(公告)号：US20120179382A1

公开(公告)日：2012-07-12

申请号：US13235612

申请日：2011-09-19

申请人： Hongxuan Zhang

发明人： Hongxuan Zhang

IPC分类号： A61B5/1455 ,  G06F19/00

CPC分类号： A61B5/14551 ,  A61B5/021 ,  A61B5/02416 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/7203 ,  A61B5/7207 ,  A61B5/7264 ,  A61B5/7282 ,  A61B5/746

摘要： A system for heart performance characterization and abnormality detection detects peaks and at least one of, a valley and a baseline comprising a substantially zero voltage level, of received signal data representing oxygen content of blood in a patient vessel over multiple heart beat cycles. The signal processor determines signal parameters including at least one of, (a) a signal amplitude magnitude between a maximum peak and minimum valley, of the received signal data, (b) a signal amplitude magnitude between a maximum peak and a baseline, of the received signal data and (c) a signal amplitude magnitude between a second highest maximum peak and minimum valley, of the received signal data. The system compares a determined signal parameter or value derived from the determined signal parameter, with a threshold value and generates an alert message associated with the threshold, in response to the comparison.

摘要翻译： 用于心脏性能表征和异常检测的系统检测峰值，并且包括基本上零电压电平的谷值和基线中的至少一个，其表示多个心跳周期中患者血液中氧含量的接收信号数据。 信号处理器确定信号参数，其包括以下中的至少一个：（a）接收信号数据的最大峰值和最小谷值之间的信号幅度幅度，（b）最大峰值和基线之间的信号幅度幅度， 接收信号数据和（c）接收信号数据的第二最高峰值和最小谷值之间的信号幅度幅度。 系统将确定的信号参数或从确定的信号参数导出的值与阈值进行比较，并且响应于该比较而产生与阈值相关联的警报消息。

公开(公告)号：US08200308B2

公开(公告)日：2012-06-12

申请号：US12171421

申请日：2008-07-11

申请人： Hongxuan Zhang ,  Detlef W. Koertge

发明人： Hongxuan Zhang ,  Detlef W. Koertge

IPC分类号： A61B5/0215 ,  A61B5/01 ,  A61B5/042

CPC分类号： A61B5/01 ,  A61B5/0422 ,  A61B18/1492 ,  A61B2018/00702 ,  A61B2018/00767 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2562/182

摘要： A catheter has a plurality of sensors and electrodes, wherein the sensors are arranged alternately and spaced apart from each other. A system for continuous measurement and mapping of physiological data may use such a catheter with a coupling unit for insulated coupling of the plurality of sensors with a measurement unit and a mapping unit for mapping values received from the sensors to a predefined matrix.

摘要翻译： 导管具有多个传感器和电极，其中传感器彼此交替布置并间隔开。 用于连续测量和映射生理数据的系统可以使用具有耦合单元的这种导管，用于将多个传感器与测量单元和映射单元绝缘耦合，用于将从传感器接收的值映射到预定矩阵。

公开(公告)号：US08139225B2

公开(公告)日：2012-03-20

申请号：US12257463

申请日：2008-10-24

申请人： Hongxuan Zhang ,  Vincent Potenzone

发明人： Hongxuan Zhang ,  Vincent Potenzone

IPC分类号： G01B9/02 ,  A61B18/22

CPC分类号： A61B5/0002 ,  A61B5/7203 ,  A61B6/04 ,  A61B6/56 ,  G06F19/3418

摘要： A device interface selectively acquires patient physiological parameter data. An acquisition processor acquires physiological data from a patient. A communication processor is coupled to an optical communication pathway for receiving a plurality of optical signals from a source. A conversion processor is electrically coupled to the acquisition processor and communication processor and converts a first optical power signal at a first frequency and received via the optical communication pathway using the communication processor, to a first electrical signal for providing power to said device interface. The conversion processor converts an optical control signal at a second frequency different from the first frequency and received via the optical communication pathway using the communication processor, to a second electrical signal for providing control data to the acquisition processor directing the acquisition processor to acquire at least one physiological parameter from a patient.

摘要翻译： 设备接口选择性地获取病人生理参数数据。 采集处理器从患者获取生理数据。 通信处理器耦合到用于从源接收多个光信号的光通信路径。 转换处理器电耦合到采集处理器和通信处理器，并且将第一频率的第一光功率信号转换并经由使用通信处理器的光通信路径接收到用于向所述设备接口提供功率的第一电信号。 转换处理器将不同于第一频率的第二频率的光控制信号通过使用通信处理器的光通信路径接收到第二电信号，用于向采集处理器提供控制数据，指示采集处理器至少获取 来自患者的一个生理参数。

公开(公告)号：US20120057674A1

公开(公告)日：2012-03-08

申请号：US13079999

申请日：2011-04-05

申请人： Hongxuan Zhang

发明人： Hongxuan Zhang

IPC分类号： A61B6/00

CPC分类号： A61B6/503 ,  A61B5/024 ,  A61B5/7285 ,  A61B6/06 ,  A61B6/4035 ,  A61B6/469 ,  A61B6/507 ,  A61B6/541 ,  A61B6/542 ,  Y10S378/901

摘要： A medical imaging system adaptively acquires anatomical images using a shape adaptive collimator including multiple different portions of X-ray absorbent material automatically adjustable to alter the dimensions of a spatial cross section of an X-ray beam of radiation into a non-rectangular shape, in response to a control signal. The synchronization processor provides a heart rate related synchronization signal derived from a patient cardiac function related parameter. The synchronization signal enables adaptive variation in timing of image acquisition within an individual heart cycle and between successive heart cycles of each individual image frame of multiple sequential image frames. The X-ray image acquisition device uses the shape adaptive collimator for acquiring anatomical images of the region of interest with reduced patient X-ray exposure in response to the synchronization signal. A display processor presents resultant images.

摘要翻译： 医学成像系统使用形状自适应准直器自适应地获取解剖图像，该形状自适应准直器包括可自动调节的X射线吸收材料的多个不同部分，以将X射线辐射束的空间横截面的尺寸改变成非矩形形状， 对控制信号的响应。 同步处理器提供从患者心脏功能相关参数导出的心率相关同步信号。 同步信号使得在单个心脏周期内以及多个连续图像帧的每个单独图像帧的连续心脏周期之间的图像获取的定时的自适应变化。 X射线图像获取装置使用形状自适应准直器，以响应于同步信号来减少患者X射线暴露来获取感兴趣区域的解剖图像。 显示处理器呈现合成图像。