公开(公告)号：US20200000761A1

公开(公告)日：2020-01-02

申请号：US16566886

申请日：2019-09-11

申请人： Huazhong Agricultural University

发明人： Xiaoyun Xu ,  Ting Wu ,  Weiwei Cao ,  Siyi Pan ,  Hui Li

IPC分类号： A61K31/216

摘要： 1,4-dicaffeoylquinic acid is used as a xanthine oxidase inhibitor and in preparation of a medicament for treating gout. The present invention is the first to isolate and identify a dicaffeoylquinic acid compound from Artemisia selengensis leaves. The compound not only has an ability of inhibiting xanthine oxidase activity, but also has the function of anti-gout inflammation, which can be better used for treating gout. The dicaffeoylquinic acid is derived from natural plants and has the advantages of being safe and non-toxic, and having fewer side effects.

公开(公告)号：US20210236451A1

公开(公告)日：2021-08-05

申请号：US17235927

申请日：2021-04-20

申请人： Huazhong Agricultural University ,  Zhiren (Wuhan) Health Industry Co., Ltd.

发明人： Xiaoyun Xu ,  Weiwei Cao ,  Ting Wu ,  Siyi Pan

IPC分类号： A61K31/216

摘要： 1,4-dicaffeoylquinic acid is used as a xanthine oxidase inhibitor and in preparation of a medicament for treating gout. The present invention is the first to isolate and identify five dicaffeoylquinic acid compounds from Artemisia selengensis leaves. The compound not only has an ability of inhibiting xanthine oxidase activity, but also has the function of anti-gout inflammation, which can be better used for treating gout. The dicaffeoylquinic acid is derived from natural plants and has the advantages of being safe and non-toxic, and having fewer side effects.

公开(公告)号：US11020367B2

公开(公告)日：2021-06-01

申请号：US16566886

申请日：2019-09-11

申请人： Huazhong Agricultural University

发明人： Xiaoyun Xu ,  Ting Wu ,  Weiwei Cao ,  Siyi Pan ,  Hui Li

IPC分类号： A61K31/216

摘要： 1,4-dicaffeoylquinic acid is used as a xanthine oxidase inhibitor and in preparation of a medicament for treating gout. The present invention is the first to isolate and identify a dicaffeoylquinic acid compound from Artemisia selengensis leaves. The compound not only has an ability of inhibiting xanthine oxidase activity, but also has the function of anti-gout inflammation, which can be better used for treating gout. The dicaffeoylquinic acid is derived from natural plants and has the advantages of being safe and non-toxic, and having fewer side effects.