公开(公告)号：US20200000761A1

公开(公告)日：2020-01-02

申请号：US16566886

申请日：2019-09-11

申请人： Huazhong Agricultural University

发明人： Xiaoyun Xu ,  Ting Wu ,  Weiwei Cao ,  Siyi Pan ,  Hui Li

IPC分类号： A61K31/216

摘要： 1,4-dicaffeoylquinic acid is used as a xanthine oxidase inhibitor and in preparation of a medicament for treating gout. The present invention is the first to isolate and identify a dicaffeoylquinic acid compound from Artemisia selengensis leaves. The compound not only has an ability of inhibiting xanthine oxidase activity, but also has the function of anti-gout inflammation, which can be better used for treating gout. The dicaffeoylquinic acid is derived from natural plants and has the advantages of being safe and non-toxic, and having fewer side effects.

公开(公告)号：US11751591B2

公开(公告)日：2023-09-12

申请号：US17013562

申请日：2020-09-05

申请人： Huazhong Agricultural University

发明人： Xiaoyun Xu ,  Ting Wu ,  Jie Song ,  Siyi Pan

IPC分类号： A23L19/20 ,  A23L33/135 ,  A23L5/20 ,  C12N1/20 ,  C12R1/01

CPC分类号： A23L19/20 ,  A23L5/28 ,  A23L33/135 ,  C12N1/205 ,  A23V2002/00 ,  C12R2001/01

摘要： A strain of Oceanobacillus picturae and applications thereof are provided, which relate to technical fields of microorganism and food processing. A strain of halophilic bacteria was screened from the brine of Xiangyang Pickled Kohlrabi and was identified as the strain of Oceanobacillus picturae by morphology, physical and chemical properties and 16S rRNA sequence. The strain is able to significantly increase the varieties and contents of volatile substances, and decrease the contents of pungent substances in pickled vegetables. The strain of Oceanobacillus picturae can improve the taste and the flavor of the pickled vegetables.

公开(公告)号：US20210236451A1

公开(公告)日：2021-08-05

申请号：US17235927

申请日：2021-04-20

申请人： Huazhong Agricultural University ,  Zhiren (Wuhan) Health Industry Co., Ltd.

发明人： Xiaoyun Xu ,  Weiwei Cao ,  Ting Wu ,  Siyi Pan

IPC分类号： A61K31/216

摘要： 1,4-dicaffeoylquinic acid is used as a xanthine oxidase inhibitor and in preparation of a medicament for treating gout. The present invention is the first to isolate and identify five dicaffeoylquinic acid compounds from Artemisia selengensis leaves. The compound not only has an ability of inhibiting xanthine oxidase activity, but also has the function of anti-gout inflammation, which can be better used for treating gout. The dicaffeoylquinic acid is derived from natural plants and has the advantages of being safe and non-toxic, and having fewer side effects.

公开(公告)号：US11020367B2

公开(公告)日：2021-06-01

申请号：US16566886

申请日：2019-09-11

申请人： Huazhong Agricultural University

发明人： Xiaoyun Xu ,  Ting Wu ,  Weiwei Cao ,  Siyi Pan ,  Hui Li

IPC分类号： A61K31/216

摘要： 1,4-dicaffeoylquinic acid is used as a xanthine oxidase inhibitor and in preparation of a medicament for treating gout. The present invention is the first to isolate and identify a dicaffeoylquinic acid compound from Artemisia selengensis leaves. The compound not only has an ability of inhibiting xanthine oxidase activity, but also has the function of anti-gout inflammation, which can be better used for treating gout. The dicaffeoylquinic acid is derived from natural plants and has the advantages of being safe and non-toxic, and having fewer side effects.