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公开(公告)号：US20090233842A1
公开(公告)日：2009-09-17
申请号：US12093437
申请日：2006-11-13
申请人： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert C. Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William E. Bunney, JR. , Marquis P. Vawter , Edward G. Jones , Prabhakara V. Choudary , Richard M. Myers , Alan F. Schatzberg , Jun Li , Devin Absher , Hiroaki Tomita
发明人： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert C. Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William E. Bunney, JR. , Marquis P. Vawter , Edward G. Jones , Prabhakara V. Choudary , Richard M. Myers , Alan F. Schatzberg , Jun Li , Devin Absher , Hiroaki Tomita
CPC分类号： C12Q1/6883 , A61K38/03 , A61K38/10 , A61K38/1774 , A61K38/1825 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , G01N33/5023 , G01N2800/304
摘要： The present application relates to the treatment and diagnosis of mood disorders, including bipolar disorder, major depression disorder and schizophrenia. The invention provides novel diagnostic markers and assays, as well as research tools for the development and discovery of agents and compounds which are useful for treating patients who suffer from mental illness.
摘要翻译： 本申请涉及心理障碍的治疗和诊断，包括双相情感障碍，重症抑郁障碍和精神分裂症。 本发明提供了新的诊断标记和测定，以及用于开发和发现可用于治疗患有精神疾病的患者的药剂和化合物的研究工具。
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2.发明申请SNP DETECTION AND OTHER METHODS FOR CHARACTERIZING AND TREATING BIPOLAR DISORDER AND OTHER AILMENTS 审中-公开表征和处理双极性疾病及其他物质的SNP检测及其他方法公开(公告)号：US20080199866A1
公开(公告)日：2008-08-21
申请号：US11868456
申请日：2007-10-05
申请人： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William Bunney , Marquis Vawter , Edward Jones , Prabhakara V. Choudary , Richard Myers , Alan Schatzberg , Jun Li , Devin Absher
发明人： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William Bunney , Marquis Vawter , Edward Jones , Prabhakara V. Choudary , Richard Myers , Alan Schatzberg , Jun Li , Devin Absher
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要： The present application relates to the use of SNPs and differential exon expression to characterize, diagnose or treat bipolar disorder and other mental illnesses, such as major depressive disorder and schizophrenia.
摘要翻译： 本申请涉及使用SNP和差异外显子表达来表征，诊断或治疗双相情感障碍和其他精神疾病，如重度抑郁障碍和精神分裂症。
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公开(公告)号：US20090019557A1
公开(公告)日：2009-01-15
申请号：US11559398
申请日：2006-11-13
申请人： Huda Akil , Stanley Watson , Simon Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert C. Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William Bunney , Marquis Vawter , Edward Jones , Prabhakara Choudary , Richard Myers , Alan Schatzberg , Jun Li , Devin Absher , Hiroaki Tomita
发明人： Huda Akil , Stanley Watson , Simon Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert C. Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William Bunney , Marquis Vawter , Edward Jones , Prabhakara Choudary , Richard Myers , Alan Schatzberg , Jun Li , Devin Absher , Hiroaki Tomita
CPC分类号： C12Q1/6883 , A61K38/03 , A61K38/10 , A61K38/1774 , A61K38/1825 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , G01N33/5023 , G01N2800/304
摘要： The present application relates to the treatment and diagnosis of mood disorders, including bipolar disorder, major depression disorder and schizophrenia. The invention provides novel diagnostic markers and assays, as well as research tools for the development and discovery of agents and compounds which are useful for treating patients who suffer from mental illness.
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4.发明申请DIFFERENTIAL METHYLATION LEVEL OF CPG LOCI THAT ARE DETERMINATIVE OF KIDNEY CANCER 审中-公开CPG的差异甲基化水平是确定KIDNEY癌症公开(公告)号：US20150218643A1
公开(公告)日：2015-08-06
申请号：US14174542
申请日：2014-02-06
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886
摘要： The present disclosure provides for and relates to the identification of novel biomarkers for diagnosis and prognosis of kidney cancer. The biomarkers of the invention show altered methylation levels of certain CpG loci relative to normal kidney tissue, as set forth.
摘要翻译： 本公开内容提供并涉及用于诊断和预后肾癌的新生物标志物的鉴定。 如上所述，本发明的生物标志物显示相对于正常肾组织的某些CpG基因座的甲基化水平改变。
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