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公开(公告)号:US08999343B2
公开(公告)日:2015-04-07
申请号:US13816894
申请日:2011-08-15
申请人: Huiquan Han , Taruna Arora , Qing Chen , Hsieng Sen Lu , Xiaolan Zhou
发明人: Huiquan Han , Taruna Arora , Qing Chen , Hsieng Sen Lu , Xiaolan Zhou
CPC分类号: C07K16/26 , A61K2039/505 , C07K16/22 , C07K2317/14 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/92 , Y02A50/466
摘要: Myostatin antagonists, including myostatin binding antibodies, are disclosed. Also disclosed are nucleic acids encoding and cells including myostatin antagonists; methods of production; and methods of use.
摘要翻译: 公开了肌生成抑制素拮抗剂,包括肌生长抑制素结合抗体。 还公开了编码核酸和包括肌肉生长抑制素拮抗剂的细胞; 生产方式; 和使用方法。
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公开(公告)号:US20130209489A1
公开(公告)日:2013-08-15
申请号:US13816894
申请日:2011-08-15
申请人: Huiquan Han , Taruna Arora , Qing Chen , Hsieng Sen Lu , Xiaolan Zhou
发明人: Huiquan Han , Taruna Arora , Qing Chen , Hsieng Sen Lu , Xiaolan Zhou
IPC分类号: C07K16/26
CPC分类号: C07K16/26 , A61K2039/505 , C07K16/22 , C07K2317/14 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/92 , Y02A50/466
摘要: There are disclosed selective myostatin antagonists (including antibodies), nucleic acids encoding them, and methods of making and using them. Neutralizing antibodies recognizing the conformational epitope near position 21 to 31 and position 50 to 60.
摘要翻译: 公开了选择性肌生成抑制素拮抗剂(包括抗体),编码它们的核酸,以及制备和使用它们的方法。 识别位置21至31位置50至60附近的构象表位的中和抗体。
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