公开(公告)号：US3652646A

公开(公告)日：1972-03-28

申请号：US3652646D

申请日：1967-03-15

申请人： ICI LTD

发明人： LEIGH THOMAS ,  THORP JEFFREY MEYRICK ,  WARING WILSON SHAW

IPC分类号： A61K31/19 ,  A61K31/165 ,  A61K31/215 ,  A61P3/06 ,  A61P9/10 ,  C07C51/00 ,  C07C51/367 ,  C07C51/41 ,  C07C59/125 ,  C07C59/68 ,  C07C59/70 ,  C07C67/00 ,  C07C69/66 ,  C07C69/712 ,  C07C205/35 ,  C07C233/02 ,  C07C313/00 ,  C07C317/00 ,  C07C317/22 ,  C07C319/14 ,  C07C323/52 ,  C07C65/00 ,  C07C69/76

CPC分类号： C07C205/35 ,  C07C51/367 ,  C07C51/412 ,  C07C59/68 ,  C07C309/00 ,  C07C317/00 ,  C07C323/00 ,  Y10S514/824 ,  Y10S516/06

摘要： BIPHENYLYLOXY-AND BIPHENYLYTHIO-ALKANOIC ACID DERIVATIVES WHICH LOWER THE CONCENTRATION OF CHOLESTEROL AND-OR TRIGLYCERIDES IN THE BLOOD SERUM AND REDUCE THE LEVEL OF FIBRINOGEN IN BLOOD PLASMA, AND WHICH POSSESS ANTI-INFLAMMATORY ACTIVITY. PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS AND A METHOD OF USING SUCH COMPOUNDS IN THE TREATMENT OF CORONOARY ARTERY DISEASE AND ATHEROSCLEROSIS.